For chemists and product formulators, a thorough understanding of the properties and specifications of chemical intermediates is fundamental to successful synthesis and product development. 4-Bromo-2-fluorobenzoic acid (CAS 112704-79-7) is a prime example of an intermediate whose characteristics dictate its utility in various applications, particularly within the pharmaceutical and agrochemical sectors.

Chemical Identity and Structure

4-Bromo-2-fluorobenzoic acid, with the molecular formula C7H4BrFO2 and a molecular weight of approximately 219.01 g/mol, is characterized by a benzene ring substituted with a bromine atom at the 4-position, a fluorine atom at the 2-position, and a carboxylic acid group. This arrangement of substituents imparts specific reactivity and physical properties, making it a valuable synthon in organic chemistry. Its CAS Number, 112704-79-7, serves as a unique identifier in global chemical databases and trade.

Key Specifications and Purity

When purchasing 4-Bromo-2-fluorobenzoic acid, industry professionals typically look for high purity levels to ensure predictable reaction outcomes and minimize by-product formation. A minimum purity of 97% is commonly specified, with many suppliers offering even higher grades. Other important physical properties include its appearance, which is typically a white to light yellow crystalline powder, and its melting point, which usually falls within the range of 211-215°C. These parameters are critical indicators of product quality and consistency, vital for both laboratory research and industrial-scale manufacturing.

Reactivity and Synthetic Utility

The presence of the bromine atom makes 4-Bromo-2-fluorobenzoic acid amenable to various palladium-catalyzed cross-coupling reactions, such as Suzuki, Sonogashira, or Buchwald-Hartwig couplings. These reactions are indispensable for forming carbon-carbon and carbon-heteroatom bonds, enabling the construction of complex biaryl systems or other functionalized aromatic compounds. The fluorine atom can influence electronic properties and metabolic stability in final products, while the carboxylic acid group can be readily converted into esters, amides, or acid chlorides, further expanding its synthetic versatility. For researchers looking to buy 4-bromo-2-fluorobenzoic acid for specific synthetic routes, understanding these reactive sites is key.

Reliable Sourcing from NINGBO INNO PHARMCHEM CO.,LTD.

As a leading manufacturer and supplier, NINGBO INNO PHARMCHEM CO.,LTD. provides detailed technical information for its chemical intermediates. Understanding the properties of 4-Bromo-2-fluorobenzoic acid empowers researchers and procurement specialists to make informed decisions. Whether you need this compound for pharmaceutical raw intermediates or agrochemical applications, partnering with a reputable supplier ensures you obtain materials that meet rigorous quality standards. They offer this crucial intermediate with guaranteed purity and comprehensive documentation, supporting your synthesis needs.

In conclusion, a deep understanding of the properties of 4-Bromo-2-fluorobenzoic acid is essential for anyone involved in its procurement or utilization. This knowledge facilitates efficient synthesis planning and ensures the successful development of advanced chemical products.