In the realm of chemical synthesis, understanding the fundamental properties of a compound is paramount to its effective utilization. 2-(2-Bromoethyl)-1,3-dioxolane (CAS 18742-02-4) is a prime example of a molecule whose well-defined properties lend themselves to a variety of important applications, particularly in the pharmaceutical and fine chemical industries. This article aims to provide a comprehensive overview of its characteristics and uses, empowering chemists and procurement professionals.

The physical appearance of 2-(2-Bromoethyl)-1,3-dioxolane is typically described as a clear, colorless to light yellow or brown liquid. This visual characteristic is often the first indicator of its physical state. Its molecular formula, C5H9BrO2, and molecular weight of approximately 181.03 g/mol are critical for stoichiometric calculations in synthesis. The boiling point is notably around 68-70 °C at 8 mmHg, indicating its relatively low volatility under vacuum, a property useful in purification processes like distillation.

Its solubility profile is also important: it is generally immiscible in water but soluble in common organic solvents. This characteristic dictates the reaction media and work-up procedures. Density, around 1.542 g/mL at 25 °C, provides further physical data for handling and formulation. The flash point, typically around 65 °C to 149 °F depending on the source, is a crucial safety parameter for storage and handling, necessitating appropriate precautions.

The primary utility of 2-(2-Bromoethyl)-1,3-dioxolane stems from its chemical reactivity. As an alkylating agent, it readily reacts with nucleophiles. This makes it an invaluable intermediate for attaching a functionalized ethyl chain to other molecules. This capability is frequently leveraged in the synthesis of complex organic compounds and, more specifically, in the creation of active pharmaceutical ingredients (APIs). Researchers and product formulators can buy this compound from reliable manufacturers to ensure the necessary purity (often specified as ≥96% or ≥99%) for their demanding applications.

The demand for high-quality 2-(2-Bromoethyl)-1,3-dioxolane drives a competitive market, with many suppliers, including those in China, offering this essential intermediate. When seeking to purchase, understanding its properties helps in evaluating supplier specifications and ensuring that the material procured aligns with the intended synthetic goals. By considering factors like purity, safety data, and application suitability, chemists can confidently integrate this versatile molecule into their workflows.