For professionals in the chemical and pharmaceutical industries, a thorough understanding of key chemical compounds is fundamental to successful research and development. 2-Fluoro-4-methyl-5-nitropyridine, identified by its CAS number 19346-47-5, is one such compound that warrants close examination due to its significant role as a synthetic intermediate.

Physically, 2-Fluoro-4-methyl-5-nitropyridine is described as a colorless liquid. This physical state is important for handling and processing within laboratories and manufacturing facilities. Its molecular formula, C6H5FN2O2, and molecular weight of 156.11 g/mol provide essential data for stoichiometric calculations in synthetic reactions. Key physical properties reported include a boiling point of approximately 254.7°C and a density around 1.357 g/cm³.

Chemically, the presence of a fluorine atom, a methyl group, and a nitro group on the pyridine ring makes 2-Fluoro-4-methyl-5-nitropyridine a versatile reactant in organic synthesis. The electron-withdrawing nature of the nitro group and the electronegativity of fluorine influence the reactivity of the pyridine ring, enabling specific substitution and coupling reactions. This reactivity profile is precisely why it is highly valued as a pharmaceutical intermediate.

The primary application of 2-Fluoro-4-methyl-5-nitropyridine is as a precursor in the synthesis of pharmaceuticals. It is utilized in the development of novel drug candidates and in the manufacturing of existing medications. Its structure allows for the efficient construction of more complex heterocyclic systems, which are common motifs in many biologically active molecules. Researchers looking to buy this compound often seek it for its utility in building complex organic structures for drug discovery.

When sourcing this chemical, it is imperative to work with reliable manufacturers and suppliers. For example, a buyer might search for '2-Fluoro-4-methyl-5-nitropyridine supplier' or 'buy 2-Fluoro-4-methyl-5-nitropyridine' to find vendors. Emphasis should be placed on purity levels, typically exceeding 99.0%, and the availability of supporting documentation such as safety data sheets (SDS) and certificates of analysis (CoA). Understanding the chemical's hazards and proper handling procedures is also critical.

The demand for high-quality pharmaceutical intermediates means that companies specializing in fine chemical manufacturing play a vital role. These manufacturers ensure that compounds like 2-Fluoro-4-methyl-5-nitropyridine meet the stringent requirements of the pharmaceutical industry. Whether for research quantities or bulk industrial supply, securing a consistent source is key.

In conclusion, 2-Fluoro-4-methyl-5-nitropyridine is a crucial compound in the chemical synthesis landscape, particularly for pharmaceutical applications. Its well-defined properties and reactivity make it an invaluable intermediate for chemists. Understanding these aspects will aid in sourcing this compound effectively from reputable suppliers and manufacturers.