For research and development scientists across various disciplines, access to well-characterized and high-quality chemical intermediates is fundamental to innovation. 2,4-Difluorobenzoic Acid (CAS: 1583-58-0) is one such compound that has garnered significant attention due to its versatile chemical structure and broad applicability, particularly in the synthesis of pharmaceuticals and advanced materials like liquid crystals.

Chemical Profile of 2,4-Difluorobenzoic Acid

2,4-Difluorobenzoic Acid is an organic compound characterized by a benzoic acid core with two fluorine atoms substituted at the ortho (2) and para (4) positions. Its molecular formula is C7H4F2O2, and it possesses a molecular weight of approximately 158.10 g/mol. The compound typically presents as a white to light yellow crystalline powder, with a melting point reported between 188-190°C. These physical properties, along with its distinct chemical reactivity stemming from the fluorine substituents and the carboxylic acid group, make it a valuable tool for synthetic chemists. The presence of fluorine atoms can impart unique electronic and lipophilic properties to molecules synthesized using this intermediate, often leading to enhanced biological activity or improved material performance.

Key Applications in Research and Development

The primary utility of 2,4-Difluorobenzoic Acid lies in its role as an intermediate in complex organic syntheses:

  • Pharmaceutical R&D: It serves as a crucial building block for the synthesis of Active Pharmaceutical Ingredients (APIs). Researchers utilize its structure to introduce fluorinated phenyl moieties into drug candidates, potentially enhancing metabolic stability, lipophilicity, and target binding affinity. When you need to buy 2,4-Difluorobenzoic Acid for your research, ensuring high purity from a reliable supplier is paramount.
  • Liquid Crystal Development: The compound is integral to the synthesis of novel liquid crystal materials used in modern display technologies. Its structural features contribute to the specific electro-optical properties required for high-performance screens.
  • Agrochemicals: While not as prominently cited as pharmaceuticals and liquid crystals, fluorinated benzoic acid derivatives can also find applications in the development of specific agrochemicals.
  • Material Science Exploration: Beyond liquid crystals, researchers explore its use in synthesizing various fluorinated polymers, specialty chemicals, and functional materials.

The Importance of Sourcing from Trusted Manufacturers

For R&D applications, the consistency and quality of chemical intermediates are non-negotiable. Researchers rely on accurate specifications and reproducible results. Therefore, sourcing 2,4-Difluorobenzoic Acid from reputable manufacturers or suppliers in China is highly recommended. These providers typically offer comprehensive documentation, including Certificates of Analysis (CoA), and maintain strict quality control protocols. When you are looking for a supplier, consider those who can provide samples for evaluation and offer competitive pricing for both small research quantities and larger bulk orders.

In conclusion, 2,4-Difluorobenzoic Acid is a versatile and important intermediate for R&D scientists. Its unique chemical properties make it an indispensable component in the synthesis of cutting-edge pharmaceuticals and advanced materials. By understanding its applications and prioritizing quality sourcing, researchers can effectively leverage this compound to drive scientific discovery and technological innovation.