In the specialized field of chemical manufacturing and research, detailed knowledge of a compound's properties and applications is crucial for effective procurement and utilization. 2'-Bromo-5'-fluoroacetophenone (CAS: 1006-33-3) is a chemical intermediate that warrants close attention due to its significance in various synthetic processes. For professionals seeking to buy this compound, understanding its physical and chemical characteristics, alongside its primary applications, will inform purchasing decisions.

This compound, with the molecular formula C8H6BrFO and a molecular weight of 217.04 g/mol, is often described as a solid. Its appearance can range from colorless to light yellow. Key physical properties reported include a boiling point of 144°C at 18 mmHg and a density of approximately 1.535 ± 0.06 g/cm³. It exhibits solubility in common organic solvents like methanol, which is a common characteristic for many organic intermediates used in synthesis.

The primary applications of 2'-Bromo-5'-fluoroacetophenone lie in its role as an intermediate for more complex molecules. It is specifically utilized in the synthesis of oxabicyclic compounds, contributing to advancements in areas requiring complex ring structures. Furthermore, its application in the enantioselective synthesis of chiral 3-aryl-1-indanone molecules is a testament to its utility in producing stereochemically pure compounds, a critical requirement in pharmaceutical development. These applications underscore its value for researchers involved in medicinal chemistry and fine chemical synthesis.

For businesses looking to purchase 2'-Bromo-5'-fluoroacetophenone, sourcing from reliable manufacturers and suppliers is paramount. China is a prominent region for chemical production, offering a wide range of intermediates at competitive prices. When searching for suppliers, using terms like '2-bromo-5-fluoroacetophenone manufacturer China,' 'buy CAS 1006-33-3,' or 'pharmaceutical intermediate price quote' will yield relevant results. It is advisable to compare quotes from multiple suppliers and to scrutinize their product specifications and quality control processes.

Understanding the safety information is also part of responsible procurement. While this compound is generally handled in controlled laboratory or industrial settings, familiarizing oneself with its safety data sheets (SDS) is recommended. By carefully considering the properties, applications, and supplier landscape, professionals can confidently purchase 2'-Bromo-5'-fluoroacetophenone to support their critical synthetic projects.