Understanding the Properties and Applications of 2-Fluoro-5-iodobenzonitrile
2-Fluoro-5-iodobenzonitrile, identified by CAS number 351003-36-6, is a compound of considerable interest in the realm of organic chemistry. Its unique combination of a fluorine atom, an iodine atom, and a nitrile group on a benzene ring makes it a highly versatile intermediate for various synthetic applications, particularly in the pharmaceutical and agrochemical industries. Understanding its detailed chemical and physical properties is key to leveraging its full potential as a building block.
Typically presented as an off-white powder, 2-Fluoro-5-iodobenzonitrile possesses a melting point range of 72-76°C, indicating its relative stability as a solid at room temperature. Its molecular formula is C7H3FIN, with a molecular weight of approximately 247.008 g/mol. The compound's density is reported around 1.9-2.0 g/cm³, and it exhibits a boiling point of approximately 253.6°C at standard atmospheric pressure. These characteristics are vital for chemists when designing reaction conditions and ensuring safe handling and storage.
The primary application of 2-Fluoro-5-iodobenzonitrile lies in its function as an intermediate in organic synthesis. The iodine substituent is particularly reactive, making it an excellent candidate for various cross-coupling reactions, such as palladium-catalyzed Suzuki, Heck, and Sonogashira couplings. These reactions are instrumental in constructing complex organic frameworks, which are the backbone of many advanced pharmaceuticals and agrochemicals. Researchers often rely on a trusted 2-Fluoro-5-iodobenzonitrile supplier in China to obtain this compound for their specific synthesis projects.
The high purity of this intermediate, typically exceeding 98.0%, is a critical factor for its successful use in sensitive synthetic pathways. When sourcing from a Chinese manufacturer, buyers can expect rigorous quality control measures. The ability to buy 2-Fluoro-5-iodobenzonitrile from a reliable source ensures consistency in experimental outcomes and facilitates scalability from laboratory research to industrial production. The common packaging of 25 kg drums also aids in managing inventory and supply chain logistics for businesses.
In summary, 2-Fluoro-5-iodobenzonitrile is an indispensable tool for modern chemists. Its well-defined properties and reactivity make it a preferred intermediate for creating specialized molecules. By understanding these aspects and partnering with experienced manufacturers, researchers and production managers can effectively utilize this compound to drive innovation in their respective fields.
Perspectives & Insights
Bio Analyst 88
“The ability to buy 2-Fluoro-5-iodobenzonitrile from a reliable source ensures consistency in experimental outcomes and facilitates scalability from laboratory research to industrial production.”
Nano Seeker Pro
“The common packaging of 25 kg drums also aids in managing inventory and supply chain logistics for businesses.”
Data Reader 7
“In summary, 2-Fluoro-5-iodobenzonitrile is an indispensable tool for modern chemists.”