For researchers and manufacturers in the chemical and pharmaceutical industries, a thorough understanding of key intermediates is vital. 4-Amino-6-chloropyrimidin-5-ylamine, identified by CAS number 4316-98-7, is one such compound, recognized for its utility in creating bioactive molecules. This article outlines its essential properties and diverse applications, guiding potential buyers on how to source this important chemical effectively.

Key Chemical and Physical Properties

4-Amino-6-chloropyrimidin-5-ylamine (C4H5ClN4) is a molecular entity with a molecular weight of 144.56 g/mol. Its physical form is typically a powder, with variations in color from white to amber, and sometimes dark green, indicating potential variations in purity or storage conditions. The melting point is reported to be around 252 °C, accompanied by decomposition, which is a critical factor during handling and high-temperature reactions. The compound exhibits limited solubility in polar organic solvents like methanol and DMSO, a common characteristic for such intermediates. Stability is a key concern, as it is noted to be hygroscopic, meaning it absorbs moisture from the air. Therefore, proper storage in sealed containers, away from moisture and under inert gas, is recommended for maintaining its quality. Manufacturers often store it under inert gas at refrigerated temperatures (2-8 °C).

Synthesis and Applications

The synthesis of 4-Amino-6-chloropyrimidin-5-ylamine typically involves the amination of precursor compounds like 4,6-dichloropyrimidin-5-amine under specific reaction conditions. Its primary value stems from its role as an intermediate in the synthesis of choloropurine derivatives. These derivatives are fundamental in the pharmaceutical industry for developing drugs with a wide spectrum of therapeutic actions, including antiviral and anticancer agents. Researchers exploring medicinal chemistry and developing novel drug candidates frequently buy 4-amino-6-chloropyrimidin-5-ylamine for their synthetic pathways.

If you are a procurement manager or a research scientist looking for this compound, understanding its application context is key. When you purchase 4-amino-6-chloropyrimidin-5-ylamine, you are acquiring a vital component for complex chemical transformations. The availability of this intermediate from reliable manufacturers and suppliers, particularly in China, offers a strategic advantage for cost-effective and scalable production.

Finding a Reliable Supplier

When seeking to source 4-Amino-6-chloropyrimidin-5-ylamine, it is crucial to identify suppliers who can guarantee purity, consistency, and timely delivery. Companies that specialize in fine chemicals and pharmaceutical intermediates are your best bet. Look for detailed product specifications, safety data sheets (SDS), and inquire about batch-to-batch consistency. Comparing the 4-amino-6-chloropyrimidin-5-ylamine price from different vendors can help optimize your procurement strategy, but always balance cost with quality and reliability. Many leading chemical companies in China are well-equipped to meet these demands, offering competitive pricing and robust supply chains.

In conclusion, 4-Amino-6-chloropyrimidin-5-ylamine (CAS 4316-98-7) is an important intermediate with specific physical and chemical properties that lend themselves to critical applications in pharmaceutical synthesis and chemical research. By focusing on quality suppliers and understanding its properties, researchers and manufacturers can effectively utilize this compound for their innovative projects.