For R&D scientists and product formulators, a deep understanding of chemical intermediates is fundamental to innovation. 4-Fluoroisoquinoline-5-sulfonyl Chloride, identified by its CAS number 194032-33-2, is a prime example of such a crucial compound. Its unique chemical structure and reactivity make it a valuable asset in organic synthesis, particularly within the pharmaceutical industry. Exploring its properties and potential applications is key for any chemist looking to buy this intermediate.

The molecular formula of 4-Fluoroisoquinoline-5-sulfonyl Chloride is C9H5ClFNO2S, with a molecular weight of approximately 245.66 g/mol. The presence of the highly electronegative fluorine atom and the reactive sulfonyl chloride group (-SO2Cl) on the isoquinoline scaffold dictates its chemical behavior. The sulfonyl chloride group is a potent electrophile, readily undergoing nucleophilic substitution reactions. This reactivity makes it an excellent starting material for creating sulfonamides, sulfonic esters, and other sulfur-containing functional groups, which are common motifs in many drug molecules.

The potential applications of 4-Fluoroisoquinoline-5-sulfonyl Chloride are broad, spanning various areas of chemical synthesis. Its utility as a building block in medicinal chemistry is particularly noteworthy. For instance, it can be employed in the synthesis of targeted therapies, where the isoquinoline core might interact with specific biological receptors, while the fluorinated and sulfonamide functionalities can enhance pharmacokinetic properties such as metabolic stability and bioavailability. Researchers often look to purchase this compound to explore novel therapeutic agents.

Furthermore, the compound’s predicted boiling point of around 360.5 ± 27.0 °C and density of 1.558 suggest it is a relatively stable solid or high-boiling liquid under standard conditions, facilitating handling and reaction processes. Safety information indicates potential hazards (GHS05, GHS07) with statements like H302 (Harmful if swallowed) and H314 (Causes severe skin burns and eye damage), underscoring the need for appropriate handling procedures and protective equipment when working with it.

For R&D scientists aiming to procure this essential intermediate, collaborating with reputable manufacturers and suppliers is vital. Companies specializing in fine chemicals and pharmaceutical intermediates, such as NINGBO INNO PHARMCHEM CO.,LTD., can provide reliable access to high-quality 4-Fluoroisoquinoline-5-sulfonyl Chloride. Understanding the material's properties and safety data allows for its effective and safe utilization in cutting-edge research and product development.