In the realm of fine chemicals and pharmaceutical intermediates, understanding the intrinsic properties and potential applications of a compound is crucial for its effective utilization. 5-Fluoro-2-oxindole (CAS 56341-41-4) is a compound that has garnered significant attention due to its utility in various synthesis pathways, particularly within the pharmaceutical industry. As a leading manufacturer and supplier, we are committed to providing detailed insights into this versatile intermediate.

5-Fluoro-2-oxindole is characterized by its appearance as an off-white to pale yellow crystalline powder. It possesses a molecular formula of C8H6FNO and a molecular weight of approximately 151.14 g/mol. Key physicochemical properties include a melting point typically ranging from 143–147°C, and it exhibits solubility in solvents like DMSO and methanol, with slight solubility in water. These characteristics are important for formulation scientists and R&D chemists when planning their synthetic routes or product development. Our commitment as a pharmaceutical intermediate manufacturer ensures these properties are maintained consistently across batches.

The synthesis of 5-Fluoro-2-oxindole often begins with a precursor such as 4-fluoroaniline. Through a sequence of reactions involving chloral hydrate, hydroxylamine hydrochloride, and cyclization under acidic conditions, followed by reduction, the target molecule is formed. Optimizing these synthesis routes for yield and purity is a core competency for any reliable 5-Fluoro-2-oxindole supplier in China. The ability to produce this compound with high purity, often exceeding 99.0%, is critical for its downstream applications.

The applications of 5-Fluoro-2-oxindole are broad, primarily serving as a key intermediate in the pharmaceutical sector. It is extensively used in the synthesis of kinase inhibitors, which are vital for treating cancers and inflammatory diseases. Its fluorinated indole structure is particularly valuable for designing molecules with enhanced binding affinity and improved metabolic stability. Furthermore, it serves as a precursor for anticancer agents and compounds being investigated for neurological applications. For procurement managers looking to buy 5-Fluoro-2-oxindole, understanding these diverse uses highlights its importance in modern chemical synthesis.

We, as a dedicated CAS 56341-41-4 supplier, ensure that our product meets stringent quality standards. Whether your interest is in 5-Fluorooxindole for Sunitinib synthesis or other advanced applications, we provide materials that are reliable and cost-effective. Our integrated manufacturing and trading approach allows us to offer competitive pricing and consistent supply, making us a preferred partner for many global research institutions and chemical companies.

In conclusion, 5-Fluoro-2-oxindole is a compound with valuable chemical properties and a wide range of applications, particularly in pharmaceutical synthesis. Its successful utilization depends on sourcing from reputable suppliers who can guarantee high purity and consistent quality. We are proud to be such a supplier, contributing to advancements in chemical research and drug development.