The chemical industry relies on a deep understanding of compound properties to drive innovation and product development. 6-Fluoroindole (CAS 399-51-9), a notable fluorinated indole derivative, exemplifies a compound with versatile applications due to its distinct physical and chemical characteristics.

Chemically identified as 6-Fluoro-1H-indole, this aromatic heterocyclic compound possesses a molecular formula of C8H6FN and a molecular weight of approximately 135.14 g/mol. Its physical appearance is typically described as a white to light yellow crystalline powder. Key physical properties include a melting point range of 72-76°C (lit.), and a boiling point of around 230°C, though estimates vary among sources. It is noted to be slightly soluble in water but readily dissolves in common organic solvents like ethanol, acetone, and dichloromethane, facilitating its use in various reaction mediums.

The presence of the fluorine atom at the 6-position significantly influences its electronic properties, often enhancing reactivity and potentially improving the biological activity of molecules synthesized from it. This makes 6-Fluoroindole a valuable intermediate for researchers in multiple fields.

In the pharmaceutical sector, 6-Fluoroindole serves as a crucial building block for synthesizing therapeutic agents. Its application is prominent in the development of compounds targeting neurological disorders and in creating potential anti-cancer drugs. Medicinal chemists frequently use this compound to introduce fluorine into lead compounds, aiming to optimize drug efficacy and pharmacokinetic profiles. When you plan to buy this intermediate, focusing on suppliers that guarantee high purity (≥98% by HPLC) is essential for successful drug discovery programs.

Beyond pharmaceuticals, 6-Fluoroindole finds utility in material science. It is employed in the synthesis of advanced materials, including organic semiconductors and polymers, where its unique electronic characteristics contribute to improved device performance. Its potential as an antimicrobial agent, by disrupting microbial quorum sensing and inhibiting biofilm formation, also opens avenues for new applications in biotechnology and health.

For those in need of this specialized chemical, sourcing from reliable manufacturers is paramount. Companies like NINGBO INNO PHARMCHEM CO.,LTD. offer high-quality 6-Fluoroindole, backed by rigorous quality control. When procuring, always verify the CAS number (399-51-9) and specifications to ensure the material meets your project's exact requirements. Exploring options from established China-based chemical suppliers often provides a balance of quality and cost-effectiveness.

In conclusion, the multifaceted properties and applications of 6-Fluoroindole make it a highly valuable compound. Whether for pharmaceutical research, organic synthesis, or material innovation, understanding its characteristics and securing a dependable source are key to leveraging its full potential.