For chemists engaged in advanced organic synthesis, a thorough understanding of the properties and synthesis routes of key intermediates is fundamental. Methyl 1-Methylpiperidine-2-Carboxylate (CAS 1690-74-0) stands out as a valuable compound, often sought after for its specific structural features and reactivity. This article aims to provide a concise overview of its characteristics and common synthesis pathways, highlighting the importance of reliable sourcing for research and industrial applications.

Methyl 1-Methylpiperidine-2-Carboxylate is characterized by its molecular formula C8H15NO2 and a molecular weight of approximately 157.21 g/mol. Physically, it is typically described as a light yellow liquid. Its CAS number, 1690-74-0, serves as a unique identifier in chemical databases and for procurement purposes. The compound features a piperidine ring, a saturated six-membered heterocycle containing one nitrogen atom, substituted at the 1-position with a methyl group and at the 2-position with a methyl ester group. This structure imbues it with specific stereochemical and electronic properties that are leveraged in downstream synthetic transformations.

Regarding its synthesis, various routes can be employed to produce Methyl 1-Methylpiperidine-2-Carboxylate. Common methods often involve the N-methylation of piperidine-2-carboxylic acid derivatives followed by esterification, or direct cyclization and functionalization steps. For example, starting materials like picolinic acid or its derivatives can undergo reduction and subsequent methylation and esterification to yield the target compound. Understanding these synthesis pathways is critical for chemists aiming to optimize yield, purity, and cost-efficiency when looking to manufacture or purchase this intermediate.

The demand for high-purity Methyl 1-Methylpiperidine-2-Carboxylate, often specified at 98% purity or higher, underscores its role in sensitive chemical processes. Sourcing this compound from reputable chemical suppliers is crucial. Manufacturers in China are often a primary source due to their capabilities in producing fine chemicals at competitive prices. For chemists and procurement specialists, identifying a trusted supplier that can guarantee consistent quality, provide detailed specifications, and offer timely delivery is key to successful project execution. When considering a purchase, always inquire about the purity, analytical methods used (e.g., GC), and the availability of samples for verification.