For chemists and R&D scientists engaged in pharmaceutical synthesis, a thorough understanding of the physical and chemical properties of their raw materials is paramount. Ethyl 4,6-dichloropyridazine-3-carboxylate (CAS 679406-03-2) is a key intermediate whose properties dictate its reactivity and suitability for various synthetic transformations. As a manufacturer and supplier committed to providing high-quality chemical intermediates, NINGBO INNO PHARMCHEM CO.,LTD. emphasizes the importance of these characteristics.

The compound is typically described as a yellow to brown oil, which offers certain advantages in handling and processing compared to solids, especially in liquid-phase reactions. Its molecular formula is C7H6Cl2N2O2, and its molecular weight is 221.041. These fundamental properties are essential for stoichiometric calculations in synthesis and for analytical characterization.

Key physical properties include its density, approximately 1.4 ± 0.1 g/cm³, and a relatively high boiling point of 353.4 ± 37.0 °C at 760 mmHg. The flash point, at 167.5 ± 26.5 °C, indicates its flammability characteristics, which are important for safe handling and storage protocols. Understanding these parameters is crucial for process chemists when designing reaction conditions and ensuring laboratory safety.

Chemically, the presence of two chlorine atoms on the pyridazine ring makes Ethyl 4,6-dichloropyridazine-3-carboxylate susceptible to nucleophilic substitution reactions. This reactivity is often exploited to introduce new functional groups and build more complex molecular architectures, which is a common strategy in API development. The ethyl ester moiety also provides a handle for further chemical modifications, such as hydrolysis to the carboxylic acid or transesterification.

For researchers looking to buy this intermediate, knowing these properties helps in planning synthesis strategies and anticipating reaction outcomes. The high assay purity (≥98.0%) offered by reliable manufacturers ensures that the desired reactivity is achieved with minimal interference from impurities. When procuring Ethyl 4,6-dichloropyridazine-3-carboxylate, especially from manufacturers in China, inquiring about detailed technical data sheets can provide valuable insights for your specific synthetic applications.