For professionals engaged in chemical synthesis and pharmaceutical development, a thorough understanding of a compound's properties and safe handling procedures is non-negotiable. 2,5-Bis(bromomethyl)pyrazine (CAS: 60023-30-5) is a potent intermediate, and like many reactive chemicals, it requires careful management. As a dedicated manufacturer and supplier, we provide essential insights into the characteristics and safety considerations for this valuable compound, ensuring its effective and secure use in your laboratory or production facility.

Key Properties of 2,5-Bis(bromomethyl)pyrazine

2,5-Bis(bromomethyl)pyrazine is known for its chemical structure and reactivity. Here are its key properties:

  • Chemical Formula: C6H6Br2N2
  • Molecular Weight: 265.93 g/mol
  • Appearance: Typically supplied as a white to off-white solid. This physical state is consistent with its molecular weight and functional groups.
  • Reactivity: The two bromomethyl groups are highly reactive, readily participating in nucleophilic substitution reactions. This is its primary utility as a synthetic intermediate.
  • Solubility: Generally soluble in common organic solvents such as dichloromethane, chloroform, and DMF. Solubility in water is typically low.
  • Stability: While stable under recommended storage conditions (cool, dry, and away from light), its reactive nature means it should be handled with care to avoid unwanted reactions or degradation.

Safe Handling and Storage Recommendations:

Proper handling is paramount when working with 2,5-Bis(bromomethyl)pyrazine. Adherence to safety protocols is crucial for personnel and laboratory integrity. We, as a responsible supplier in China, always recommend the following:

  • Personal Protective Equipment (PPE): Always wear appropriate PPE, including chemical-resistant gloves (e.g., nitrile), safety goggles or a face shield, and a lab coat. Work in a well-ventilated area, preferably a fume hood, to avoid inhalation of any dust or vapors.
  • Avoid Contact: Prevent contact with skin, eyes, and clothing. If contact occurs, wash the affected area immediately with plenty of water and seek medical advice if irritation persists.
  • Handling Procedures: When weighing or transferring the solid, do so carefully to minimize dust generation. Use appropriate tools like spatulas.
  • Storage Conditions: Store 2,5-Bis(bromomethyl)pyrazine in a tightly sealed container in a cool, dry, and well-ventilated place. Protection from light is also advisable. Keep it away from incompatible materials such as strong oxidizing agents, strong bases, and moisture.
  • Disposal: Dispose of waste material according to local environmental regulations. Do not pour down drains.

Procurement Considerations for Safety and Quality

When you buy 2,5-Bis(bromomethyl)pyrazine, ensure your supplier provides a comprehensive Safety Data Sheet (SDS) that details all hazards, handling, storage, and emergency procedures. The quality of the product is also linked to its safety; impurities can sometimes lead to unexpected reactions. Therefore, sourcing from reputable manufacturers in China who guarantee high purity and provide detailed product information is essential. This ensures both the safety of your operations and the success of your synthesis projects.

By understanding and respecting the properties and handling requirements of 2,5-Bis(bromomethyl)pyrazine, chemists can confidently incorporate this versatile intermediate into their synthetic strategies, fostering innovation in chemical and pharmaceutical research.