For chemists and researchers utilizing advanced organic synthesis techniques, understanding the specific properties and handling requirements of key reagents is fundamental. 3-Chloro-4-methoxyphenylboronic acid (CAS: 175883-60-0) is a prime example of such a compound, serving as a versatile organic synthesis building block. This article aims to provide crucial information on its characteristics and best practices for its use and storage.

Physically, 3-Chloro-4-methoxyphenylboronic acid typically presents as an off-white powder. This solid form facilitates handling and accurate weighing, essential for reproducible chemical reactions. Its melting point, often cited around 238-242°C (lit.), is an indicator of its purity. Chemically, the presence of the boronic acid moiety (-B(OH)2) makes it reactive in various transformations, most notably in palladium-catalyzed cross-coupling reactions like the Suzuki-Miyaura coupling. The chlorine atom and methoxy group on the phenyl ring also influence its reactivity and regioselectivity in further chemical modifications.

Proper storage is critical to maintain the integrity and efficacy of 3-Chloro-4-methoxyphenylboronic acid. As a boronic acid intermediate, it can be sensitive to moisture and air. Therefore, it is generally recommended to store it in a cool, dry, and well-ventilated place, preferably in a tightly sealed container. Many suppliers, particularly reputable 3-Chloro-4-methoxyphenylboronic acid manufacturers, advise storage at 2-8°C to prevent degradation. Adhering to these conditions ensures that when you buy 3-Chloro-4-methoxyphenylboronic acid, you are receiving a product that will perform reliably in your applications.

When incorporating this compound into synthesis, understanding its role as a pharmaceutical intermediate or a component in fine chemicals is key. Whether you are a seasoned chemist or a procurement specialist looking to buy organic synthesis building blocks, seeking information from your 3-Chloro-4-methoxyphenylboronic acid supplier in China regarding safe handling and storage protocols is always a good practice. Proper knowledge ensures both the longevity of the material and the safety of laboratory operations.