For chemists and engineers working with 3-Oxocyclobutane-1-carboxylic acid (CAS 23761-23-1), a thorough understanding of its physical and chemical properties, along with proper handling and storage procedures, is crucial for safe and effective use. This intermediate, widely employed in pharmaceutical synthesis and organic chemistry, requires careful management to maintain its integrity and ensure workplace safety.

3-Oxocyclobutane-1-carboxylic acid is typically presented as an off-white solid. Its melting point is reported to be in the range of 69-70°C, indicating it is a stable solid at standard room temperatures. The compound exhibits moderate solubility, being slightly soluble in water but generally more soluble in common organic solvents. Its molecular formula is C5H6O3, with a molecular weight of 114.10 g/mol. These physical characteristics are important considerations for its application in reactions and for choosing appropriate storage conditions.

Chemically, 3-Oxocyclobutane-1-carboxylic acid possesses both a ketone and a carboxylic acid functional group. These groups offer reactive sites for a variety of synthetic transformations. The carboxylic acid moiety can undergo esterification, amidation, or salt formation, while the ketone group is susceptible to nucleophilic addition reactions, reduction, or enolate chemistry. This versatility makes it a valuable building block for constructing complex molecular architectures, particularly in the pharmaceutical industry for creating APIs.

When handling 3-Oxocyclobutane-1-carboxylic acid, it is essential to adhere to standard laboratory safety practices. Protective equipment such as gloves, safety glasses, and laboratory coats should be worn. Adequate ventilation is also important, especially when working with powdered forms, to prevent inhalation of dust. The compound is classified with hazard statements indicating it may cause skin irritation (H315), serious eye irritation (H319), and respiratory irritation (H335). Therefore, direct contact and inhalation should be minimized.

Storage recommendations typically advise keeping the compound in a cool, dry place, away from direct sunlight and incompatible materials, such as strong oxidizing agents. Containers should be kept tightly closed to prevent moisture absorption and contamination. For bulk purchases, understanding the supplier's recommended storage conditions and shelf life is also beneficial.

As a trusted supplier of specialized chemicals, we provide detailed technical data, including safety information and handling guidelines, for 3-Oxocyclobutane-1-carboxylic acid. If you are looking to buy this intermediate or require further information on its properties, please do not hesitate to contact us. Our team is dedicated to supporting your chemical needs with high-quality products and comprehensive support.