Benzenesulfonyl Chloride (CAS 98-09-9) is a chemical compound that plays a significant role across various industrial sectors, from pharmaceuticals to dyes. As a leading supplier, NINGBO INNO PHARMCHEM CO.,LTD. believes it's essential for our clients to have a comprehensive understanding of its properties, applications, and safe handling procedures. This knowledge is crucial for efficient utilization and ensuring workplace safety.

Physical Properties:

Benzenesulfonyl Chloride is typically described as a light yellow transparent liquid. This visual characteristic is important for initial identification. Its density is approximately 1.384 g/mL at 25°C, and it has a relatively high boiling point of around 251.5°C, although it can decompose at this temperature. It is insoluble in water but readily soluble in common organic solvents such as alcohol and ether. Its refractive index (n20/D) is around 1.551.

Chemical Properties and Reactivity:

The chemical nature of Benzenesulfonyl Chloride is defined by its sulfonyl chloride group. This group makes it a reactive electrophile. It is known to react with nucleophiles containing active N-H and O-H bonds, such as amines and alcohols, to form sulfonamides and sulfonate esters, respectively. This reactivity is the foundation of its utility as a synthetic intermediate.

However, this reactivity also means it requires careful handling. Benzenesulfonyl Chloride is sensitive to moisture and will hydrolyze in water, particularly hot water, producing corrosive and toxic hydrochloric acid and benzenesulfonic acid. For this reason, it should be stored in tightly closed containers in a cool, dry, and well-ventilated area, away from direct sunlight and heat sources. Incompatible materials include strong oxidizing agents, strong bases, and certain organic compounds like methyl formamide and dimethyl sulfoxide, with which it can react vigorously or even explosively.

Safe Handling and Storage:

Given its corrosive nature and potential for vigorous reactions, proper safety protocols are paramount when working with Benzenesulfonyl Chloride. It can cause severe skin and eye irritation or burns. Inhalation of vapors can be harmful. Therefore, it is essential to wear appropriate personal protective equipment (PPE), including chemical-resistant gloves, safety goggles or face shields, and protective clothing. Work should be conducted in a well-ventilated area or under a fume hood. In case of contact, immediate flushing with plenty of water is recommended, followed by medical attention.

Industrial Significance:

Despite its reactive nature, Benzenesulfonyl Chloride is a vital intermediate for numerous industrial applications. Its use in preparing sulfonamides makes it crucial for the pharmaceutical industry, while its role in dye synthesis highlights its importance in the textile and colorant sectors. It also finds application in the agrochemical industry for pesticide production.

NINGBO INNO PHARMCHEM CO.,LTD. is committed to providing high-quality Benzenesulfonyl Chloride (CAS 98-09-9) with a purity of 99.5%. We ensure proper packaging (250kg/drum) and handling guidelines are followed to maintain product integrity. We encourage all our clients to review safety data sheets (SDS) and to consult with our technical team for any specific handling or storage queries. Contact us to buy Benzenesulfonyl Chloride and ensure you are sourcing from a reliable and knowledgeable supplier.