For professionals in the chemical and pharmaceutical industries, a deep understanding of key intermediates is vital for successful product development and manufacturing. 5-Bromothiophene-3-carboxylic acid (CAS: 100523-84-0) is one such compound, distinguished by its chemical properties, synthesis methods, and broad applicability. As a sought-after building block, knowing how to efficiently source it from reliable manufacturers is crucial.

Physically, 5-Bromothiophene-3-carboxylic acid typically appears as a white to off-white powder, with a purity often exceeding 99% for specialized applications. Its melting point and boiling point are important parameters for handling and reaction planning. The compound’s reactivity stems from the interplay between the electron-withdrawing bromine atom and the carboxylic acid functional group on the thiophene ring, enabling participation in a wide array of organic reactions, including cross-coupling reactions and esterification.

The synthesis of 5-Bromothiophene-3-carboxylic acid commonly involves the bromination of 3-thiophenecarboxylic acid. This process, often carried out in glacial acetic acid with bromine, yields the desired product after purification steps like filtration and recrystallization. Many manufacturers in China specialize in optimizing these synthesis routes to ensure high yields and purity, making them preferred suppliers for global buyers.

When you are looking to buy 5-Bromothiophene-3-carboxylic acid, consider the advantages offered by direct sourcing from Chinese manufacturers. These suppliers often provide detailed product specifications, safety data sheets (SDS), and certificates of analysis (CoA), ensuring compliance and quality assurance. Whether for laboratory research or industrial-scale production, choosing a supplier that can offer flexible packaging and consistent delivery is key to a successful procurement strategy.