Understanding the Properties and Safe Handling of 6-Chloro-1-hydroxybenzotriazole
For any chemical compound to be effectively and safely utilized, a thorough understanding of its properties and handling requirements is essential. 6-Chloro-1-hydroxybenzotriazole (Cl-HOBt), a compound vital for applications in peptide synthesis, materials science, and organic chemistry, is no exception. NINGBO INNO PHARMCHEM CO.,LTD. provides this crucial intermediate and emphasizes the importance of informed usage.
Cl-HOBt, with the CAS number 26198-19-6, typically presents as a white to off-white crystalline powder. Its melting point is generally reported in the range of 190-200°C, indicating a relatively stable solid form under standard conditions. Chemically, its structure features a benzotriazole ring system with a hydroxyl group and a chlorine atom, which contributes to its reactivity and utility as a coupling agent and stabilizer. While described as stable under recommended storage conditions, like many fine chemicals, it requires careful handling to maintain its purity and efficacy.
Proper storage is critical for preserving the quality of Cl-HOBt. It is generally recommended to store the compound in a cool, dry, and well-ventilated area, away from direct sunlight and sources of ignition. Keeping containers tightly sealed is crucial to prevent moisture absorption, which can affect its performance. For certain applications or extended storage, refrigeration might be advised, as indicated by specific supplier guidelines. NINGBO INNO PHARMCHEM CO.,LTD. ensures that its products are packaged appropriately for transport and initial storage, but users must adhere to best practices for long-term preservation.
In terms of safety, while Cl-HOBt is classified with a warning signal word and hazard statements indicating potential harm if ingested, its handling generally follows standard laboratory and industrial chemical safety protocols. This includes wearing appropriate personal protective equipment (PPE) such as gloves, eye protection, and laboratory coats. Avoiding inhalation of dust and ensuring adequate ventilation in work areas are also key precautions. Understanding the specific Safety Data Sheet (SDS) provided by the manufacturer is the definitive guide for safe handling and emergency procedures.
By prioritizing knowledge of its properties and adhering to safe handling practices, users can maximize the benefits derived from 6-Chloro-1-hydroxybenzotriazole. NINGBO INNO PHARMCHEM CO.,LTD. is committed to providing not only high-quality products but also the necessary information to support safe and effective utilization of our chemical intermediates.
Cl-HOBt, with the CAS number 26198-19-6, typically presents as a white to off-white crystalline powder. Its melting point is generally reported in the range of 190-200°C, indicating a relatively stable solid form under standard conditions. Chemically, its structure features a benzotriazole ring system with a hydroxyl group and a chlorine atom, which contributes to its reactivity and utility as a coupling agent and stabilizer. While described as stable under recommended storage conditions, like many fine chemicals, it requires careful handling to maintain its purity and efficacy.
Proper storage is critical for preserving the quality of Cl-HOBt. It is generally recommended to store the compound in a cool, dry, and well-ventilated area, away from direct sunlight and sources of ignition. Keeping containers tightly sealed is crucial to prevent moisture absorption, which can affect its performance. For certain applications or extended storage, refrigeration might be advised, as indicated by specific supplier guidelines. NINGBO INNO PHARMCHEM CO.,LTD. ensures that its products are packaged appropriately for transport and initial storage, but users must adhere to best practices for long-term preservation.
In terms of safety, while Cl-HOBt is classified with a warning signal word and hazard statements indicating potential harm if ingested, its handling generally follows standard laboratory and industrial chemical safety protocols. This includes wearing appropriate personal protective equipment (PPE) such as gloves, eye protection, and laboratory coats. Avoiding inhalation of dust and ensuring adequate ventilation in work areas are also key precautions. Understanding the specific Safety Data Sheet (SDS) provided by the manufacturer is the definitive guide for safe handling and emergency procedures.
By prioritizing knowledge of its properties and adhering to safe handling practices, users can maximize the benefits derived from 6-Chloro-1-hydroxybenzotriazole. NINGBO INNO PHARMCHEM CO.,LTD. is committed to providing not only high-quality products but also the necessary information to support safe and effective utilization of our chemical intermediates.
Perspectives & Insights
Logic Thinker AI
“provides this crucial intermediate and emphasizes the importance of informed usage.”
Molecule Spark 2025
“Cl-HOBt, with the CAS number 26198-19-6, typically presents as a white to off-white crystalline powder.”
Alpha Pioneer 01
“Its melting point is generally reported in the range of 190-200°C, indicating a relatively stable solid form under standard conditions.”