Understanding the Properties and Synthesis of 2-Phenoxyaniline for Industrial Use
For professionals in the chemical industry, a thorough understanding of a compound's properties and synthesis is fundamental to its effective application. 2-Phenoxyaniline (CAS 2688-84-8), a vital aromatic amine, possesses specific physicochemical characteristics that dictate its utility in various industrial sectors, from pharmaceuticals to advanced materials. NINGBO INNO PHARMCHEM CO.,LTD., as a dedicated chemical intermediate supplier, aims to provide clear information for our B2B clients.
Physical and Chemical Properties: 2-Phenoxyaniline is typically described as a light yellow to brown crystalline solid, with a melting point generally between 48-52°C and a boiling point around 320°C. Its molecular formula is C12H11NO, and its molecular weight is approximately 185.23 g/mol. Solubility is a key consideration; it is soluble in common organic solvents like ethanol and ether but generally insoluble in water. This solubility profile influences its handling, purification, and integration into different reaction media. Understanding these properties is crucial for formulators and chemists when planning synthetic routes and process conditions.
Synthesis Routes: While specific proprietary methods exist, common industrial synthesis of 2-Phenoxyaniline often involves the Ullmann condensation or related coupling reactions. These typically involve the reaction of an aniline derivative with a halobenzene or phenol derivative under catalytic conditions. For instance, reacting 2-aminophenol with bromobenzene or aniline with 2-bromophenol in the presence of a base and copper catalyst can yield 2-Phenoxyaniline. Advances in green chemistry are also leading to more efficient and environmentally friendly synthesis pathways. For businesses looking to buy 2-Phenoxyaniline, it's beneficial to inquire about the supplier's manufacturing processes and quality control to ensure product consistency.
When selecting a 2-Phenoxyaniline manufacturer, especially one based in China, it's important to ensure they have robust synthetic capabilities and quality assurance protocols. NINGBO INNO PHARMCHEM CO.,LTD. is committed to providing high-purity 2-Phenoxyaniline, backed by detailed technical specifications and reliable batch-to-batch consistency. Our expertise in producing this key intermediate supports your R&D and manufacturing needs, offering a dependable source for your chemical requirements.
Perspectives & Insights
Bio Analyst 88
“Synthesis Routes: While specific proprietary methods exist, common industrial synthesis of 2-Phenoxyaniline often involves the Ullmann condensation or related coupling reactions.”
Nano Seeker Pro
“These typically involve the reaction of an aniline derivative with a halobenzene or phenol derivative under catalytic conditions.”
Data Reader 7
“For instance, reacting 2-aminophenol with bromobenzene or aniline with 2-bromophenol in the presence of a base and copper catalyst can yield 2-Phenoxyaniline.”