3-(2-Methoxy-5-methylphenyl)-3-phenylpropanoic acid (CAS 109089-77-2) is a fine chemical intermediate widely recognized for its utility in organic synthesis, particularly within the pharmaceutical sector. As a key component in the manufacturing of various APIs, understanding its properties and synthesis methods is crucial for researchers and procurement specialists. This article outlines the key attributes and typical production pathways for this compound.

Physicochemically, 3-(2-Methoxy-5-methylphenyl)-3-phenylpropanoic acid typically appears as a white crystalline powder. Its molecular formula is C17H18O3, with a molecular weight of approximately 270.32 g/mol. Key properties include a melting point range often cited around 130-132°C, and good solubility in common organic solvents such as DMF and Methanol, while exhibiting limited solubility in water. These characteristics are vital for its handling, purification, and application in synthetic reactions.

The synthesis of this compound generally involves multi-step organic reactions. Common approaches include forming the substituted phenyl intermediate and then introducing the propanoic acid side chain. One widely used method involves amide intermediate reduction followed by acid formation, offering good selectivity. Another common strategy is base-mediated hydrolysis of ester or halogenated precursors, often monitored by HPLC for optimal yield and purity. Researchers often select methods that balance yield, purity, and cost-effectiveness, making manufacturers' specific protocols a key consideration when sourcing.

For businesses looking to purchase 3-(2-Methoxy-5-methylphenyl)-3-phenylpropanoic acid, it is essential to engage with reputable suppliers who can guarantee consistent product quality and provide detailed technical data. Direct sourcing from manufacturers often ensures competitive pricing and a more reliable supply chain. When inquiring about this chemical, specifying the required purity and quantity will facilitate a more accurate quote and efficient service, ensuring you obtain the precise material needed for your demanding applications.