For chemists, formulators, and procurement specialists in the chemical and pharmaceutical sectors, a deep understanding of key intermediates is vital. 4-Hydroxythiobenzamide, identified by CAS 25984-63-8, is one such compound that warrants detailed examination due to its significant utility.

Chemically, 4-Hydroxythiobenzamide is characterized as a light yellow powder with a melting point typically in the range of 191-193°C. Its molecular formula is C7H7NOS, with a molecular weight of 153.2. The compound is known to be soluble in solvents like DMSO and methanol, albeit slightly. These physical and chemical properties are essential for handling, storage, and effective use in various chemical reactions and formulations. As a supplier, providing accurate specification sheets is a core part of our service.

The synthesis of 4-Hydroxythiobenzamide is an area of active interest, particularly for achieving high yields and purity. One common method involves reacting 4-cyanophenol with sodium hydrosulfide and a secondary amine in an aqueous medium, followed by the dropwise addition of an organic weak acid. This process, detailed in various patents, aims to efficiently convert readily available starting materials into the desired thiobenzamide derivative. For manufacturers looking to buy 4-Hydroxythiobenzamide, understanding these synthesis routes can inform quality assessments and discussions with suppliers.

The applications of 4-Hydroxythiobenzamide are diverse and impactful. Its primary recognized use is as a critical intermediate in the synthesis of Febuxostat, a drug used to manage gout by lowering uric acid levels. Beyond this, its structure lends itself to the creation of various heterocyclic compounds, making it a valuable building block in medicinal chemistry for developing new therapeutic agents, including potential CDK5 inhibitors for neurodegenerative diseases. Furthermore, its ability to absorb specific wavelengths of light has led to its exploration in materials science for developing polymers with tailored optical properties.

For professionals seeking to procure 4-Hydroxythiobenzamide, partnering with a reliable manufacturer and supplier is key. Our commitment as a producer of this fine chemical ensures that you receive a product of consistent quality, backed by technical data and responsive support. We aim to be your trusted source, providing the essential chemical intermediates you need to drive innovation and production forward.