For chemists and researchers in the fields of pharmaceuticals, agrochemicals, and materials science, a deep understanding of key chemical intermediates is crucial for driving innovation. 5-Fluoro-2-iodobenzoic acid, with the CAS number 52548-63-7, is a prime example of such an intermediate, offering a unique combination of chemical reactivity and structural features.

The molecule's structure is characterized by a benzoic acid core substituted with a fluorine atom at the 5-position and an iodine atom at the 2-position. This specific arrangement of halogens imparts distinct chemical properties. The fluorine atom can influence the electron density of the aromatic ring and alter the compound's lipophilicity and metabolic stability, making it attractive for pharmaceutical applications. The iodine atom, being a good leaving group, makes 5-Fluoro-2-iodobenzoic acid an excellent substrate for a variety of cross-coupling reactions, such as Suzuki-Miyaura, Sonogashira, and Heck couplings. These reactions are fundamental in constructing complex organic molecules and are widely used in both research laboratories and industrial settings.

A common synthesis route for 5-Fluoro-2-iodobenzoic acid involves the diazotization of 2-Amino-5-fluorobenzoic acid, followed by treatment with a source of iodide, often in the presence of a catalyst like copper(I) iodide. This method leverages readily available starting materials to produce the desired intermediate with good yields. For procurement managers seeking to buy 5-Fluoro-2-iodobenzoic acid, understanding these synthetic pathways can provide insight into potential impurity profiles and the manufacturing expertise of a potential pharmaceutical intermediate manufacturer.

The purity of the compound is a critical parameter, with specifications typically requiring ≥98%. When sourcing from a 5-Fluoro-2-iodobenzoic acid supplier in China, it is important to verify the analytical data, such as NMR spectra and HPLC chromatograms, that confirm its identity and purity. Evaluating the CAS 52548-63-7 price should always be done in the context of these quality assurances and the supplier's overall reliability.

As a versatile organic synthesis building block, 5-Fluoro-2-iodobenzoic acid is a valuable asset for any chemist. Whether you are developing new pharmaceuticals, designing novel agrochemicals, or exploring advanced materials, this compound offers a gateway to intricate molecular designs. We are a dedicated supplier committed to providing high-quality chemical intermediates, including 5-Fluoro-2-iodobenzoic acid, to support your scientific and industrial endeavors. Contact us to discuss your specific requirements and receive a competitive quote.