For research and development chemists, understanding the fundamental properties and synthesis routes of key chemical intermediates is essential for successful project execution. 4,4,4-Trifluoro-1-phenylbutane-1,3-dione (BTA) is a prime example of such an intermediate, highly valued for its versatility in organic synthesis and its unique chemical profile. This guide aims to provide R&D chemists with critical insights into BTA's characteristics and how to best source it.

BTA, with the CAS number 326-06-7, presents as a white to yellow crystalline solid with a low melting point (typically 38-40°C). Its molecular formula C10H7F3O2 and molecular weight of 216.16 g/mol hint at its complex structure. The presence of the electron-withdrawing trifluoromethyl group adjacent to a carbonyl significantly influences its reactivity, making it a potent electrophile and a source of acidic protons. This duality allows BTA to participate in a wide range of chemical transformations, from nucleophilic additions to various condensation reactions.

The synthesis of BTA can be achieved through several established methods, often involving the Claisen condensation or related reactions. Typically, a trifluoroacetyl source, such as ethyl trifluoroacetate, is reacted with a phenyl-containing precursor under basic conditions. Achieving high yields and purity requires careful control of reaction parameters and subsequent purification steps. For R&D chemists needing reliable quantities, sourcing from a manufacturer that specializes in efficient synthesis is paramount. If you are looking to buy BTA, explore options from manufacturers with proven track records.

BTA's applications are broad, ranging from its critical role in synthesizing fluorinated pharmaceuticals and agrochemicals to its use in developing advanced materials and functional polymers. Its ability to introduce the trifluoromethyl moiety imparts desirable properties like enhanced lipophilicity, metabolic stability, and thermal resistance. For efficient procurement, consider partnering with a trusted supplier that offers detailed technical specifications and competitive pricing. NINGBO INNO PHARMCHEM CO.,LTD. is a prominent manufacturer and supplier of BTA in China, dedicated to supporting the R&D community.

In summary, grasping the properties and synthesis of 4,4,4-Trifluoro-1-phenylbutane-1,3-dione is fundamental for R&D chemists. Its versatile reactivity and the advantageous properties it imparts make it an invaluable intermediate. For reliable access to high-quality BTA, consider the offerings from NINGBO INNO PHARMCHEM CO.,LTD., your go-to source for essential chemical building blocks. We are ready to provide the BTA needed to drive your research forward.