For researchers and procurement specialists in the pharmaceutical sector, understanding the precise specifications and purity of chemical intermediates is fundamental to successful drug development. 5-Fluoro-2-Hydroxy-3-Nitropyridine (CAS 136888-20-5) is a prime example of such a compound, where detailed knowledge of its properties can inform purchasing decisions. This article highlights the critical specifications to consider when you aim to buy this key pharmaceutical intermediate.

The chemical identity of 5-Fluoro-2-Hydroxy-3-Nitropyridine is confirmed by its CAS number, 136888-20-5, molecular formula C5H3FN2O3, and molecular weight of approximately 158.09 g/mol. Physically, it is described as a light yellow to yellow solid. However, the most critical specification for its use as a pharmaceutical intermediate is its purity level. Reputable manufacturers typically offer this compound with a purity of 98% or higher, often verified by techniques such as High-Performance Liquid Chromatography (HPLC).

A purity of 98%+ ensures that the compound possesses the necessary chemical integrity for complex synthesis reactions. Lower purity levels can introduce unwanted side reactions, reduce yields, and potentially contaminate the final pharmaceutical product, leading to costly reworks or failed batches. Therefore, when you consider purchasing from a supplier, always request a Certificate of Analysis (CoA) that clearly states the purity and the analytical methods used for its determination.

Other important specifications may include information on solubility, storage conditions, and potential hazards, all of which are detailed in the Safety Data Sheet (SDS). Understanding these aspects helps ensure safe handling and effective use. For procurement managers, comparing the technical specifications and purity data from different manufacturers is a vital step in the process of requesting a quote.

In conclusion, when sourcing 5-Fluoro-2-Hydroxy-3-Nitropyridine, paying close attention to purity and detailed specifications is paramount. By partnering with a reliable manufacturer or supplier that provides comprehensive documentation, you can confidently purchase this essential intermediate, ensuring the quality and success of your pharmaceutical research and development projects. Always inquire about the specific purity levels and analytical data available from your chosen vendor.