In the realm of pharmaceutical manufacturing and fine chemical synthesis, the quality of raw materials and intermediates is non-negotiable. N-(Benzyloxycarbonyl)-DL-tert-Leucine Methyl Ester, identified by CAS number 141971-09-7, is a prime example of an intermediate where precise purity and well-defined specifications are paramount. Understanding these aspects is crucial for any buyer aiming to ensure the efficacy and safety of their final products.

Why Purity Matters for CAS 141971-09-7

N-(Benzyloxycarbonyl)-DL-tert-Leucine Methyl Ester, with its molecular formula C15H21NO4, is often used as a building block in complex synthetic pathways. Impurities, even in trace amounts, can:

  • Interfere with Reactions: Impurities can act as catalysts or inhibitors, leading to unintended side reactions, reduced yields, or the formation of unwanted by-products.
  • Compromise Final Product Quality: If an intermediate is impure, these impurities can carry through the synthesis, contaminating the final Active Pharmaceutical Ingredient (API) and potentially affecting its therapeutic profile or causing adverse effects in patients.
  • Increase Purification Costs: Removing unwanted impurities from the final product can be an expensive and time-consuming process. Starting with a high-purity intermediate significantly reduces these downstream costs.

Key Specifications to Verify When Buying

When procuring N-(Benzyloxycarbonyl)-DL-tert-Leucine Methyl Ester, buyers should meticulously review the product specifications provided by the manufacturer or supplier. Key specifications typically include:

  • Assay/Purity: This indicates the percentage of the target compound present. For pharmaceutical intermediates, purity levels are often expected to be 98% or higher, often verified by techniques like HPLC (High-Performance Liquid Chromatography) or GC (Gas Chromatography).
  • Moisture Content: Water can affect the stability and reactivity of chemical compounds. Specifying a maximum allowable moisture content is common.
  • Appearance: While not always a primary indicator of purity, the described physical appearance (e.g., color, form) should match expectations.
  • Specific Impurity Profiles: Some applications may require strict limits on certain known impurities. Manufacturers should be able to provide data on these if necessary.
  • CAS Number Confirmation: Always double-check that the CAS number provided (141971-09-7) corresponds to the exact chemical you intend to purchase.

Ensuring Quality Through Supplier Due Diligence

To guarantee that you receive N-(Benzyloxycarbonyl)-DL-tert-Leucine Methyl Ester meeting your exact requirements, it is essential to select suppliers who are transparent about their quality control measures. Requesting a Certificate of Analysis (CoA) for each batch is standard practice. This document details the analytical testing performed and confirms that the product meets the stated specifications. Partnering with reputable manufacturers and suppliers known for their commitment to quality assurance is the most effective way to secure high-quality intermediates for your pharmaceutical synthesis needs.