Understanding the Purity and Specifications of (S)-2-(tert-butoxycarbonylamino)-3-(3-(methylsulfonyl)phenyl)propanoic Acid
For professionals in the pharmaceutical and fine chemical industries, understanding the precise specifications of chemical intermediates is not just a detail—it's a critical factor influencing the success of synthesis, the efficacy of the final product, and overall project viability. (S)-2-(tert-butoxycarbonylamino)-3-(3-(methylsulfonyl)phenyl)propanoic acid (CAS 1289646-76-9) is a prime example of a specialized compound where purity and well-defined characteristics are non-negotiable.
The chemical structure itself, C15H21NO6S with a molecular weight of approximately 343.4 g/mol, indicates a complex organic molecule. The designation '(S)' is of utmost importance, signifying its specific chiral configuration. In many pharmaceutical applications, only one enantiomer (the S-form or R-form) will exhibit the desired biological activity, while the other might be inactive or even detrimental. Therefore, sourcing this compound with high enantiomeric purity is crucial. Manufacturers typically aim for a purity level of 98% or higher, with precise control over the unwanted enantiomer.
The appearance of (S)-2-(tert-butoxycarbonylamino)-3-(3-(methylsulfonyl)phenyl)propanoic acid is commonly described as a light yellow to yellow solid. This physical characteristic, while seemingly minor, can be an initial indicator of quality and consistency. Deviations in color or physical form might suggest variations in synthesis or storage conditions, prompting further investigation.
For procurement managers and R&D scientists, the 'purity' of a chemical intermediate like this one refers to several aspects. It typically encompasses chemical purity (the absence of unrelated chemical impurities from the synthesis process) and enantiomeric purity (the ratio of the desired S-enantiomer to the R-enantiomer). Suppliers like NINGBO INNO PHARMCHEM CO.,LTD. emphasize their ability to deliver this compound with a guaranteed purity of 98%. This level of assurance is vital for processes where even trace impurities can interfere with reactions, lead to side products, or compromise the final API's regulatory compliance.
When requesting a quote or placing an order for CAS 1289646-76-9, it is advisable to confirm not just the purity percentage but also the analytical methods used for its determination (e.g., HPLC, GC, NMR). Understanding the CAS number and molecular formula ensures that you are ordering the exact compound required. For those looking to buy this specific intermediate, partnering with a manufacturer that provides comprehensive technical documentation, including detailed CoAs, is key to ensuring successful and reproducible outcomes in your synthesis projects. The reliability of a chemical supplier is directly tied to their ability to consistently meet these stringent purity and specification requirements.
Perspectives & Insights
Nano Explorer 01
“It typically encompasses chemical purity (the absence of unrelated chemical impurities from the synthesis process) and enantiomeric purity (the ratio of the desired S-enantiomer to the R-enantiomer).”
Data Catalyst One
“This level of assurance is vital for processes where even trace impurities can interfere with reactions, lead to side products, or compromise the final API's regulatory compliance.”
Chem Thinker Labs
“When requesting a quote or placing an order for CAS 1289646-76-9, it is advisable to confirm not just the purity percentage but also the analytical methods used for its determination (e.”