Polyvinylpyrrolidone (PVP) K17 is a lower molecular weight grade of PVP, known for its good solubility and moderate film-forming properties. While grades like K30 and K90 often take center stage for their strong binding and solubilizing capabilities, PVP K17 plays a crucial, albeit sometimes understated, role in pharmaceutical manufacturing. Its specific properties make it ideal for niche applications such as enhancing drug solubility for certain formulations and acting as a flow aid in capsule filling. NINGBO INNO PHARMCHEM CO.,LTD., a prominent manufacturer and supplier of pharmaceutical excipients in China, offers high-quality PVP K17 to meet these specialized needs.

PVP K17 as a Solubilizer for Specific Drugs

While higher molecular weight PVPs are generally more effective as strong binders or for dramatic solubility increases, PVP K17 can be an excellent choice for specific drug molecules. Its lower viscosity in solution means it can be easily incorporated into liquid formulations where high concentrations of the polymer might be detrimental to flow properties. For drugs that require a moderate boost in solubility or where the drug molecule can effectively complex with the lower molecular weight polymer, PVP K17 offers a targeted solution. Its hydrophilic nature still allows it to aid in the dispersion and dissolution of certain APIs, particularly when used in combination with other solubilizing agents or in specific liquid dosage forms.

PVP K17 as a Flow Aid for Capsules and Powders

One of the significant applications of PVP K17 in pharmaceutical manufacturing is its use as a flow aid. Pharmaceutical powders, especially those with poor flow characteristics, can cause significant issues during capsule filling and tablet compression, leading to dosage uniformity problems and production inefficiencies. By incorporating a small percentage of PVP K17, often as a dilute alcoholic solution that is then dried onto the powder particles, manufacturers can improve the flowability and bulk density of the powder mixture. This granulation-like effect achieved through PVP K17 coating helps the powder flow more smoothly and consistently into the die cavities or capsules, ensuring accurate dosing and reducing manufacturing downtime.

This application is particularly beneficial for powders used in hard capsules. By improving the powder's ability to flow, PVP K17 aids in achieving consistent fill weights, which is critical for product quality and regulatory compliance. Manufacturers looking to optimize their powder handling processes can significantly benefit from purchasing and utilizing PVP K17.

Acquiring Quality PVP K17 from a Trusted Source

NINGBO INNO PHARMCHEM CO.,LTD. is a dedicated manufacturer and supplier of pharmaceutical-grade PVP K17 in China. We understand the specific requirements for pharmaceutical excipients and ensure our products meet the necessary purity and performance standards. For companies seeking to enhance their formulation processes, particularly in achieving better powder flow or specific solubilization effects, sourcing quality PVP K17 is key. We offer competitive pricing for bulk purchases and are equipped to meet the demands of global pharmaceutical manufacturers. Contact us today to learn more about our PVP K17 offerings and how we can support your manufacturing needs.