In the pharmaceutical industry, the quality of every raw material and intermediate directly impacts the safety and efficacy of the final drug product. Methyl 4-(butyrylamino)-3-methyl-5-nitrobenzoate (CAS 152628-01-8) is a prime example of such a critical intermediate, primarily used in the synthesis of Telmisartan. Ensuring its consistent quality is therefore a non-negotiable aspect for any pharmaceutical manufacturer or contract research organization (CRO).

When seeking to purchase Methyl 4-(butyrylamino)-3-methyl-5-nitrobenzoate, it's essential to partner with suppliers who implement rigorous quality assurance (QA) measures. A reputable manufacturer will not only guarantee high purity (often specified as ≥98%) but will also provide comprehensive documentation. This typically includes a detailed Certificate of Analysis (COA) for each batch, which verifies key physical and chemical properties, including assay, impurity profiles, and often spectral data like NMR or IR.

The role of a robust QA system extends to the entire supply chain. This means verifying that the intermediate is manufactured under controlled conditions, often adhering to Good Manufacturing Practices (GMP) principles, even if the intermediate itself isn't the final API. For those looking to buy Methyl 4-(butyrylamino)-3-methyl-5-nitrobenzoate, inquiring about the supplier's quality management system and their adherence to international standards like ISO is crucial.

Furthermore, the chemical's stability during storage and transport is a key quality consideration. Suppliers should provide clear storage recommendations, such as keeping the compound at 2-8°C and protected from light and moisture. A trustworthy supplier will also have well-defined procedures for handling any quality-related issues or deviations, ensuring that potential problems are addressed promptly and effectively.

For procurement professionals, comparing the price offered by various suppliers should be balanced with their commitment to quality. Investing in a slightly higher-priced but consistently high-quality intermediate can prevent costly rejections, production delays, and potential regulatory issues down the line. As a key pharmaceutical intermediate, the integrity of Methyl 4-(butyrylamino)-3-methyl-5-nitrobenzoate directly influences the integrity of the final API. Therefore, prioritizing QA from your chosen manufacturer is a critical business decision.