Quality Assurance: Sourcing High-Purity 4-(oxolan-2-yloxy)butan-1-ol
In the demanding fields of pharmaceutical development and fine chemical synthesis, the purity and consistency of raw materials are non-negotiable. 4-(Oxolan-2-yloxy)butan-1-ol, known by its CAS number 64001-06-5, is a critical intermediate that requires stringent quality control. For procurement managers and researchers, understanding how to ensure the quality of this compound when buying, especially from international manufacturers, is paramount.
The specifications for 4-(oxolan-2-yloxy)butan-1-ol often highlight a purity of 97%+. This high level of purity is essential because even minor impurities can significantly impact the outcome of complex organic synthesis reactions or the efficacy of a final pharmaceutical product. Chemical manufacturers typically provide detailed analytical data, such as High-Performance Liquid Chromatography (HPLC) or Gas Chromatography (GC) reports, to verify purity. When you decide to buy this compound, always request these documents.
The molecular formula C8H16O3 and molecular weight of 160.21 provide the fundamental identity of the chemical. However, beyond these basic parameters, understanding physical properties like predicted density (1.04±0.1 g/cm³) and boiling point (260.0±35.0 °C) can also indirectly speak to the quality and consistency of the manufacturing process. For instance, a consistent boiling range suggests a well-controlled synthesis and purification.
When sourcing from manufacturers, particularly in regions like China, it's vital to look for established companies with robust quality assurance systems. This includes adherence to Good Manufacturing Practices (GMP) where applicable, even for intermediates. A reliable supplier will not only offer competitive pricing but also transparency regarding their manufacturing processes and quality control measures. Requesting a free sample is a crucial step to perform in-house quality checks before placing larger orders for 4-(oxolan-2-yloxy)butan-1-ol.
Furthermore, understanding the compound's role as a pharmaceutical intermediate and its potential use as an impurity reference highlights the need for meticulously characterized materials. By prioritizing quality assurance and working with trusted manufacturers, organizations can guarantee that their supply of 4-(oxolan-2-yloxy)butan-1-ol meets the rigorous standards required for successful research, development, and production.
Perspectives & Insights
Silicon Analyst 88
“For instance, a consistent boiling range suggests a well-controlled synthesis and purification.”
Quantum Seeker Pro
“When sourcing from manufacturers, particularly in regions like China, it's vital to look for established companies with robust quality assurance systems.”
Bio Reader 7
“This includes adherence to Good Manufacturing Practices (GMP) where applicable, even for intermediates.”