Ensuring the quality and purity of chemical intermediates is paramount for the success of any research and development project, especially in sensitive fields like peptide synthesis and pharmaceutical manufacturing. Sarcosine Methyl Ester Hydrochloride (CAS 13515-93-0) is a critical compound, and understanding its quality control parameters is vital for researchers and procurement specialists alike.

Sarcosine Methyl Ester Hydrochloride, a white to beige crystalline powder, requires rigorous analytical testing to confirm its identity, purity, and suitability for intended applications. Reputable manufacturers and suppliers employ a suite of quality control (QC) measures to guarantee that their product meets stringent industry standards. These measures typically include verifying the compound’s physical characteristics, chemical composition, and the absence of harmful impurities.

Key quality control parameters for Sarcosine Methyl Ester Hydrochloride include:

  • Purity Assessment: High-Performance Liquid Chromatography (HPLC) is the standard method for determining the purity of Sarcosine Methyl Ester Hydrochloride. A purity of 98% or higher is often required for demanding applications like peptide synthesis, ensuring that side reactions are minimized. The analysis identifies and quantifies any related substances, such as the parent compound, sarcosine, or other potential synthesis byproducts.
  • Identity Confirmation: Techniques like Nuclear Magnetic Resonance (NMR) spectroscopy and Mass Spectrometry (MS) are used to confirm the molecular structure and identity of the compound. Proton NMR will show characteristic peaks for the N-methyl, methylene, and methyl ester groups, while Mass Spectrometry confirms the molecular weight.
  • Residual Solvent Analysis: Gas Chromatography (GC) is typically employed to detect and quantify any residual solvents from the synthesis process. Methanol is a common solvent used in esterification, and its residual levels must be within acceptable limits, usually specified in parts per million (ppm).
  • Water Content: Due to its hygroscopic nature, the water content is an important parameter. Karl Fischer titration is the preferred method for accurate water determination, ensuring the material has not absorbed excessive moisture during handling or storage.
  • Physical Appearance: Visual inspection confirms the expected appearance, such as color (white to beige) and physical state (crystalline powder), which can be an initial indicator of quality.

For procurement managers looking to buy Sarcosine Methyl Ester Hydrochloride, it is crucial to partner with suppliers who transparently provide detailed Certificates of Analysis (CoA) for each batch. This document should clearly state the results of all QC tests performed. Working with a trusted manufacturer or supplier, particularly one with robust quality systems and a history of consistent product delivery, is paramount. This diligence ensures that the Sarcosine Methyl Ester Hydrochloride procured will perform reliably in critical applications.

When seeking to purchase this essential intermediate, prioritizing suppliers who emphasize stringent quality control measures will ultimately lead to more successful research outcomes and efficient manufacturing processes. The investment in high-quality Sarcosine Methyl Ester Hydrochloride is an investment in the reliability and reproducibility of your scientific endeavors. As a dedicated provider, we ensure our Sarcosine Methyl Ester Hydrochloride meets the highest purity standards, supporting your critical R&D needs.