In the chemical industry, particularly for applications in pharmaceuticals and fine chemicals, the quality and consistency of raw materials are non-negotiable. 3,5-Diaminobenzoic Acid (DABA), a versatile organic intermediate with CAS 535-87-5, is no exception. For R&D scientists and procurement specialists, understanding the key specifications and evaluating supplier quality control processes is essential. This guide focuses on what to look for when sourcing DABA.

Key Specifications for 3,5-Diaminobenzoic Acid
When procuring DABA, several critical parameters define its suitability for specific applications:

  • Assay/Purity: This is the most crucial specification. For pharmaceutical intermediates and high-end chemical synthesis, purity levels of 98% or 99% (often determined by HPLC) are typically required. Technical grades might be sufficient for less sensitive applications, usually at around 97% purity. Always verify the analytical method used for purity determination.
  • Appearance: DABA is generally described as a white to gray powder or crystalline solid. Consistency in color and form across different batches can indicate good manufacturing practices.
  • Melting Point: The specified melting point range (typically 235-238°C with decomposition) serves as a quick check for purity and identity. Deviations can signal the presence of impurities.
  • Solubility: DABA is known for its good solubility in water. Understanding its solubility in various organic solvents relevant to your synthesis is also important.
  • Moisture Content: For hygroscopic or moisture-sensitive reactions, the specified maximum moisture content is critical.
  • Ash Content/Residue on Ignition: Low ash content indicates minimal inorganic impurities, important for many chemical syntheses.
  • Impurity Profile: Beyond overall purity, understanding the specific impurities present and their concentrations is vital, especially for pharmaceutical applications where even trace impurities can have significant effects. Suppliers should ideally provide detailed COAs with impurity data.

Evaluating Supplier Quality Control
Beyond the product specifications themselves, evaluating a supplier's quality control (QC) system is paramount. When selecting a 3,5-Diaminobenzoic Acid manufacturer, consider:

  • Certifications: ISO certifications (e.g., ISO 9001) demonstrate a commitment to quality management systems. GMP compliance may be necessary for pharmaceutical intermediates.
  • Analytical Capabilities: Does the supplier have well-equipped laboratories with advanced analytical instruments (HPLC, GC, NMR, etc.)? Do they regularly calibrate their equipment?
  • Documentation: Can the supplier readily provide comprehensive documentation such as Certificates of Analysis (COA) for each batch, Material Safety Data Sheets (MSDS), and potentially route of synthesis (ROS) or method of analysis (MOA)?
  • Batch-to-Batch Consistency: A reliable supplier will demonstrate consistent quality across different production batches. Obtaining samples and conducting your own verification tests is highly recommended.
  • Traceability: A robust QC system ensures full traceability of raw materials and production processes for each batch.

For businesses looking to buy DABA, partnering with suppliers who prioritize stringent quality control and provide transparent documentation ensures that you receive a product that meets your exact needs, ultimately contributing to the success and safety of your own downstream products. Investigating reputable chemical suppliers, particularly those with a strong presence in China, is a key step in this process.