In the demanding field of pharmaceutical research and manufacturing, the quality of chemical intermediates is not just a preference but a fundamental requirement. Ethyl 1H-pyrrolo[2,3-b]pyridine-2-carboxylate, identified by CAS number 221675-35-0, is one such intermediate where quality plays a pivotal role. This article underscores why discerning buyers prioritize high-purity, well-specified materials when looking to purchase this compound.

Ethyl 1H-pyrrolo[2,3-b]pyridine-2-carboxylate (Molecular Formula: C10H10N2O2, Molecular Weight: 190.2) is a sophisticated heterocyclic molecule utilized as a building block in the synthesis of various Active Pharmaceutical Ingredients (APIs). The commonly cited purity level of 99% minimum is critical. Impurities, even in trace amounts, can lead to unintended side reactions, reduced yields, difficulties in purification of the final API, and, most importantly, potential safety concerns for patients. Therefore, any procurement decision must start with a stringent evaluation of the supplier's quality assurance processes.

Beyond purity, other specifications are equally important for successful application. For instance, understanding the physical state and recommended storage conditions helps maintain the integrity of the compound. While specific appearance details are often provided, proper storage (sealed, dry, room temperature) is universally advised. Furthermore, knowing its predicted boiling point (436.4±37.0 °C) aids in process design and safety protocols. When you buy this intermediate, ensure your supplier provides comprehensive technical data.

Sourcing Ethyl 1H-pyrrolo[2,3-b]pyridine-2-carboxylate from reliable manufacturers, particularly those in China, can offer a balance of quality and cost-effectiveness. However, the emphasis must remain on quality. A competitive price point is attractive, but it should never compromise the product’s purity or consistency. Procurement managers should actively seek suppliers who provide detailed Certificates of Analysis (CoA) for each batch, confirming that the material meets the stated specifications.

The consistent availability of high-quality CAS 221675-35-0 is also a critical factor for manufacturers. Establishing a relationship with a dependable supplier ensures a stable supply chain, preventing disruptions in production timelines. This reliability is often a hallmark of suppliers who are deeply invested in quality control and customer satisfaction, making them ideal partners for long-term collaborations.

In conclusion, when purchasing Ethyl 1H-pyrrolo[2,3-b]pyridine-2-carboxylate, quality must be the paramount consideration. Prioritizing purity, detailed specifications, and a reputable supplier’s commitment to quality assurance will ultimately lead to more successful drug development and manufacturing outcomes. Always choose a supplier that champions quality, ensuring your investment in this vital intermediate is well-placed.