For researchers and development scientists, the availability of high-quality chemical reagents at competitive prices is crucial for advancing their work. Fmoc-(R)-3-Amino-5-hexenoic acid (CAS 269726-95-6) is a widely used chiral building block in organic synthesis, particularly for peptide chemistry and pharmaceutical research. Understanding the factors that influence its quality and pricing can help procurement professionals and bench chemists make informed purchasing decisions. This guide focuses on what to look for when you need to buy this important compound and how to secure the best value from suppliers.

Key Quality Indicators for Fmoc-(R)-3-Amino-5-hexenoic Acid

When sourcing Fmoc-(R)-3-Amino-5-hexenoic acid, prioritize suppliers who clearly specify and guarantee the following quality aspects:

  • Purity: The most critical indicator is purity, often stated as a percentage (e.g., ≥97%). High purity is essential for ensuring accurate reaction outcomes and avoiding unwanted side products, especially in sensitive synthesis routes. Always request a Certificate of Analysis (CoA) to confirm the purity and identity of the compound.
  • Enantiomeric Purity: As a chiral molecule, the enantiomeric purity (or enantiomeric excess, ee) of the (R)-isomer is also vital. Impurities of the (S)-isomer can lead to undesired stereoisomers in your final product, which may have different biological activities or properties.
  • Appearance: The typical appearance is a white to off-white solid or powder. Variations in color or form might indicate potential degradation or the presence of impurities.
  • Solubility and Stability: Information on solubility in common solvents and storage recommendations (e.g., refrigerated, inert atmosphere) is important for proper handling and maintaining the compound's integrity.

Understanding Pricing Factors and Obtaining Quotes

The price of Fmoc-(R)-3-Amino-5-hexenoic acid can vary significantly based on several factors:

  • Quantity: As with most chemicals, the unit price generally decreases with larger purchase quantities due to economies of scale in production and packaging.
  • Purity Grade: Higher purity grades or specific enantiomeric excess requirements may command higher prices.
  • Supplier Origin: Manufacturers from different regions may have varying cost structures. Suppliers based in China often offer competitive pricing due to efficient manufacturing processes.
  • Lead Time and Customization: Rush orders or custom synthesis requirements can also influence the price.

To get the best price when you need to buy Fmoc-(R)-3-Amino-5-hexenoic acid, it is recommended to obtain multiple quotes from different suppliers. Clearly specify your requirements for purity and quantity. Engaging with established chemical manufacturers and distributors who specialize in amino acids and peptide synthesis reagents can ensure you receive a quality product at a competitive price, backed by reliable service. If you are a researcher looking for a dependable source, consider reaching out to specialized chemical suppliers to discuss your needs and obtain the best possible value.