The pharmaceutical industry relies on a steady supply of high-quality intermediates to produce life-saving and life-enhancing medications. One such critical intermediate is (S)-2-(1,6,7,8-Tetrahydro-2H-indeno[5,4-b]furan-8-yl)ethylamine, commonly known by its CAS number 196597-81-6. This chiral amine is an indispensable precursor in the synthesis of Ramelteon, a medication widely prescribed for insomnia. For pharmaceutical manufacturers and R&D chemists, understanding where and how to buy this compound efficiently is crucial. This article explores the importance of sourcing this intermediate and provides guidance for procurement professionals.

The Significance of (S)-2-(1,6,7,8-Tetrahydro-2H-indeno[5,4-b]furan-8-yl)ethylamine in Drug Synthesis

(S)-2-(1,6,7,8-Tetrahydro-2H-indeno[5,4-b]furan-8-yl)ethylamine (C13H17NO, MW: 203.280) is characterized by its distinct indeno-furan structure and the presence of an ethylamine group with specific (S) stereochemistry. This stereochemical integrity is vital, as it directly influences the pharmacological activity of the final drug product, Ramelteon. Ramelteon functions by selectively targeting melatonin receptors in the suprachiasmatic nucleus, regulating the body's circadian rhythm. Any deviation in the intermediate's structure or purity can compromise the efficacy and safety of the final API. Therefore, R&D scientists often search for terms like 'Ramelteon intermediate manufacturer' or 'high purity CAS 196597-81-6 for sale' when initiating their sourcing process.

The typical specification of this intermediate is a colorless liquid with an assay of ≥98.0%. Pharmaceutical companies must ensure their suppliers consistently deliver material that meets these exact requirements. Requesting detailed specifications and supplier reliability information is a standard practice for any serious buyer.

Navigating the Market: Sourcing from China

China has emerged as a global hub for chemical manufacturing, including a vast array of pharmaceutical intermediates. For a compound like (S)-2-(1,6,7,8-Tetrahydro-2H-indeno[5,4-b]furan-8-yl)ethylamine, sourcing from a reputable Chinese manufacturer can offer significant advantages in terms of cost-effectiveness and scalability. Procurement managers actively look for 'buy (S)-2-(1,6,7,8-Tetrahydro-2H-indeno[5,4-b]furan-8-yl)ethylamine China' to identify potential suppliers.

When evaluating potential suppliers, consider these factors:

  • Quality Assurance: Verify the supplier's commitment to quality through certifications and adherence to international standards. A Certificate of Analysis (CoA) for each batch is essential.
  • Production Capacity: Ensure the manufacturer can meet your volume requirements, whether for pilot studies or large-scale commercial production. Inquire about 'bulk purchase price' and 'supply ability'.
  • Technical Support: A responsive supplier offering technical assistance and detailed product information is invaluable.
  • Logistics and Delivery: Understand their shipping capabilities and timelines to ensure timely delivery for your production schedules.

The Supplier's Role in Your Success

As a dedicated manufacturer and supplier, we pride ourselves on providing consistent quality and reliable supply of (S)-2-(1,6,7,8-Tetrahydro-2H-indeno[5,4-b]furan-8-yl)ethylamine. Our advanced manufacturing processes ensure the high purity and correct stereochemistry required for your Ramelteon synthesis. We understand the competitive landscape and strive to offer competitive 'price for (S)-2-(1,6,7,8-Tetrahydro-2H-indeno[5,4-b]furan-8-yl)ethylamine' without compromising on quality. We support pharmaceutical companies by simplifying the procurement process, allowing R&D chemists and production teams to focus on their core objectives.

Conclusion

Securing a dependable source for critical pharmaceutical intermediates like (S)-2-(1,6,7,8-Tetrahydro-2H-indeno[5,4-b]furan-8-yl)ethylamine is fundamental to the success of pharmaceutical manufacturing. By partnering with experienced and quality-focused suppliers, companies can ensure the integrity of their API production. We encourage R&D professionals and procurement specialists to consider our capabilities as a trusted manufacturer and supplier. Please reach out to us for quotes, samples, or further information on how we can support your needs.