Ranolazine CAS 95635-55-5: Application in Anti-Ischemic Drug Development
For pharmaceutical researchers and product formulators, understanding the precise applications of key chemical intermediates is vital for successful drug development. Ranolazine, identified by CAS number 95635-55-5, is a compound of significant interest in the field of cardiovascular medicine, particularly for its anti-ischemic properties. This article delves into the specific applications of Ranolazine, offering insights for R&D scientists and procurement professionals looking to purchase this essential material from reliable manufacturers.
Ranolazine functions as a selective inhibitor of the late sodium current (late INa). This mechanism is crucial in conditions like myocardial ischemia, where prolonged sodium influx contributes to cellular dysfunction and impaired cardiac contractility. By reducing this sustained sodium influx, Ranolazine helps to prevent intracellular calcium overload, thereby preserving cellular energy metabolism and improving cardiac function during ischemic events. This makes it a prime candidate for use in drugs targeting angina and other related conditions.
The development of novel anti-anginal drugs often requires sourcing intermediates with guaranteed high purity. When you look to buy Ranolazine, understanding its molecular structure (C24H33N3O4) and ensuring a high purity level, often above 99%, is critical. Manufacturers in China specializing in fine chemicals and pharmaceutical intermediates play a significant role in providing these materials at competitive price points. For scientists, knowing where to find a consistent supplier of Ranolazine is as important as understanding its therapeutic potential.
Beyond its direct anti-ischemic effects, Ranolazine has also been studied for its impact on cellular energy metabolism. Research indicates it can shift myocardial energy production towards glucose oxidation, which is more oxygen-efficient than fatty acid oxidation, especially under ischemic conditions. This metabolic modulation further contributes to its cardioprotective effects. These insights are valuable for R&D teams exploring new therapeutic strategies for heart disease.
For procurement teams, identifying a dependable Ranolazine manufacturer involves evaluating their production capacity, quality control systems, and export experience. We, as a dedicated supplier and manufacturer in China, focus on delivering Ranolazine that meets international quality standards. Whether you are initiating new research projects or scaling up existing formulations, our ability to provide detailed product specifications and timely quotations ensures a smooth procurement process. Exploring options to purchase Ranolazine in bulk is a common strategy for cost optimization in pharmaceutical manufacturing.
In summary, Ranolazine (CAS 95635-55-5) is a pivotal pharmaceutical intermediate with significant applications in the development of anti-ischemic and anti-anginal therapies. Researchers and manufacturers seeking to buy this compound should prioritize high purity and a reliable supply chain from experienced producers. Our company is committed to being your trusted source for Ranolazine, supporting your advancements in cardiovascular drug development.
Perspectives & Insights
Data Seeker X
“Ranolazine functions as a selective inhibitor of the late sodium current (late INa).”
Chem Reader AI
“This mechanism is crucial in conditions like myocardial ischemia, where prolonged sodium influx contributes to cellular dysfunction and impaired cardiac contractility.”
Agile Vision 2025
“By reducing this sustained sodium influx, Ranolazine helps to prevent intracellular calcium overload, thereby preserving cellular energy metabolism and improving cardiac function during ischemic events.”