The pharmaceutical industry relies heavily on specialized chemical intermediates to synthesize life-changing medications. One such crucial compound is 1-(2,3-Dichlorophenyl)piperazine, identified by its CAS number 41202-77-1. This molecule serves as a fundamental building block, particularly in the complex synthesis pathways leading to Aripiprazole, a key drug used in treating various psychiatric conditions including schizophrenia and bipolar disorder.

Chemical Profile and Significance

1-(2,3-Dichlorophenyl)piperazine, often abbreviated as DCPP, possesses a molecular formula of C10H12Cl2N2. Its structure, featuring a dichlorinated phenyl group attached to a piperazine ring, makes it an ideal starting material for introducing specific functionalities into larger drug molecules. The presence of the two chlorine atoms on the phenyl ring and the reactive nitrogen atoms within the piperazine moiety allow for precise chemical modifications essential for building the Aripiprazole molecule.

Synthesis Pathway Insights

The synthesis of Aripiprazole typically involves a multi-step process, and DCPP is a pivotal intermediate. Its successful incorporation into the Aripiprazole structure ensures the development of a drug with specific pharmacological properties, including its partial agonism at dopamine D2 and serotonin 5-HT1A receptors. For pharmaceutical companies and contract manufacturing organizations (CMOs), ensuring a consistent and high-quality supply of DCPP is therefore critical for the efficient production of Aripiprazole.

Procurement Strategies for DCPP Suppliers

When seeking to buy 1-(2,3-Dichlorophenyl)piperazine, it is imperative to partner with reliable manufacturers and suppliers. Sourcing from reputable chemical companies, particularly those based in major manufacturing hubs like China, can provide access to products with guaranteed purity (often exceeding 99.0% by HPLC) and competitive pricing. Procurement managers should look for suppliers who can offer comprehensive documentation, such as Certificates of Analysis (CoA), and demonstrate a strong understanding of the regulatory requirements within the pharmaceutical sector. The ability to provide both small quantities for research and development and large bulk orders for commercial production is also a key indicator of a capable supplier.

Why Choose a Dedicated Supplier?

The importance of DCPP in the pharmaceutical supply chain cannot be overstated. As a specialized chemical intermediate, its availability and quality directly influence the production schedules and outcomes of critical medications. Therefore, establishing a relationship with a dependable manufacturer or supplier that specializes in pharmaceutical intermediates is a strategic imperative. Companies looking for a consistent source of 1-(2,3-Dichlorophenyl)piperazine for their Aripiprazole synthesis projects should proactively seek out suppliers offering both technical expertise and robust supply chain solutions. We encourage you to contact us for a quote or to request a sample of our high-purity DCPP.