In the intricate landscape of pharmaceutical development, specific chemical intermediates serve as the foundational blocks upon which life-saving medications are built. 1,3-Dichloro-4-fluorobenzene, identified by its CAS number 1435-48-9, stands out as one such crucial compound. This article delves into the significance of this molecule for R&D scientists and product formulators, emphasizing its applications and the importance of sourcing it from reliable manufacturers and suppliers.

1,3-Dichloro-4-fluorobenzene: A Versatile Chemical Intermediate

With the chemical formula C6H3Cl2F and a molecular weight of 164.99, 1,3-Dichloro-4-fluorobenzene is a halogenated aromatic compound characterized by its clear, colorless to yellow liquid appearance. Its unique structure, featuring both chlorine and fluorine atoms on a benzene ring, imparts specific reactivity that is highly valued in complex organic synthesis. Its typical melting point of -23 °C and boiling point of 172-174 °C make it manageable for laboratory and industrial processes.

Applications in Pharmaceutical R&D

The primary utility of 1,3-Dichloro-4-fluorobenzene lies in its role as a key intermediate for synthesizing a wide array of pharmaceuticals. Notably, it serves as a precursor in the production of certain broad-spectrum antibiotics, which are critical in combating bacterial infections. For R&D scientists, having access to high-purity 1,3-Dichloro-4-fluorobenzene is essential for:

  • Developing Novel APIs: Its structure allows for further functionalization, enabling the creation of new molecular entities with potential therapeutic benefits.
  • Optimizing Synthesis Pathways: Understanding the reactivity of this intermediate helps in designing efficient and cost-effective synthesis routes for existing and new drugs.
  • Ensuring Product Quality: Using high-grade 1,3-Dichloro-4-fluorobenzene from trusted suppliers minimizes impurities in the final API, which is crucial for regulatory approval and patient safety.

When scientists are looking to buy this intermediate, they often seek specific purity levels, typically 98% or higher, to ensure reproducible results in their experiments.

Sourcing Strategies for R&D Professionals

For scientists and formulators looking to purchase 1,3-Dichloro-4-fluorobenzene, several sourcing strategies can ensure success:

  • Direct Manufacturer Partnerships: Engaging directly with a reputable manufacturer, especially one in China, can provide a direct line to the product, potentially offering better pricing and technical support.
  • Specialty Chemical Suppliers: Reputable chemical distribution companies can also be a valuable source, often maintaining stock for faster delivery of research quantities.
  • Inquire about Availability and Price: Always contact potential suppliers to confirm stock levels and obtain current price quotes, whether for small research batches or larger quantities.

The consistent availability of high-quality 1,3-Dichloro-4-fluorobenzene from dependable manufacturers is vital for the progression of pharmaceutical research. By carefully selecting their suppliers, R&D scientists can ensure the integrity of their work and accelerate the discovery and development of new medicines.