The advancement of chemical synthesis is often propelled by the availability of specific, well-characterized building blocks that enable the creation of complex and functional molecules. 1-Benzothiophene-5-carboxylic Acid (CAS: 2060-64-2) is one such compound, playing an increasingly important role as a versatile intermediate in pharmaceutical research, organic chemistry, and material science. Understanding its chemical profile and application potential is key for scientists and procurement professionals aiming to innovate.

1-Benzothiophene-5-carboxylic Acid is a heterocyclic organic compound characterized by the fusion of a benzene ring and a thiophene ring, with a carboxylic acid group appended at the 5-position of the benzothiophene system. Its unique structure, represented by the molecular formula C9H6O2S and a molecular weight of 178.21 g/mol, provides a robust platform for diverse synthetic manipulations. Typically supplied as a white solid, it exhibits a high melting point of approximately 207-208°C, indicating good thermal stability. The presence of the carboxylic acid moiety grants it acidic properties, with a predicted pKa of around 4.13, allowing for typical acid-based reactions such as salt formation, esterification, and amide coupling.

The primary significance of 1-Benzothiophene-5-carboxylic Acid lies in its extensive use as a key intermediate in the synthesis of pharmaceuticals. Its benzothiophene core is a prevalent structural feature in numerous biologically active compounds, making this acid an ideal starting material for drug discovery and development. Researchers frequently look to buy 1-benzothiophene-5-carboxylic acid to incorporate this scaffold into potential drug candidates, aiming to achieve specific pharmacological activities. Beyond pharmaceuticals, it also finds applications in the synthesis of advanced materials and specialty chemicals, where its specific structural attributes are leveraged for desired properties.

For professionals seeking to procure this essential compound, efficient sourcing is critical. Identifying a reliable manufacturer and supplier is key to ensuring quality and consistent availability. Chinese chemical companies are prominent players in the global supply of such intermediates, often offering high-purity grades (e.g., 95% min) at competitive price points. When searching for this chemical, using precise terms such as '1-Benzothiophene-5-carboxylic acid price' or 'CAS 2060-64-2 for sale' will help narrow down the options. It is advisable to request detailed product specifications, safety data sheets (MSDS), and Certificates of Analysis (CoA) from prospective suppliers. These documents are crucial for quality assurance and regulatory compliance.

Establishing a working relationship with a trusted supplier in China can offer significant advantages, including potential for bulk purchasing and consistent supply chain management. Many providers offer excellent customer support, assisting with technical queries and providing tailored solutions. When you decide to purchase this intermediate, consider the supplier's responsiveness and their ability to meet your specific packaging and delivery requirements. This proactive approach ensures that your research and production cycles are not interrupted by supply issues.

In conclusion, 1-Benzothiophene-5-carboxylic Acid is an indispensable intermediate in modern chemical synthesis, particularly valued in the pharmaceutical industry for its structural versatility. By prioritizing quality, engaging with reputable suppliers, and understanding the compound's chemical properties, researchers and manufacturers can effectively utilize this building block to drive innovation and achieve scientific breakthroughs.