The field of medicinal chemistry continuously seeks novel compounds with therapeutic potential, particularly in the fight against viral infections and cancers. Nucleoside analogs represent a cornerstone of these efforts, mimicking natural nucleosides to interfere with vital biological processes. At the heart of synthesizing many advanced nucleoside analogs lies a critical intermediate: 1-Chloro-3,5-di-(4-chlorobenzoyl)-2-deoxy-D-ribose (CAS 21740-23-8). This highly functionalized molecule serves as a versatile building block for researchers pushing the boundaries of drug discovery.

For R&D scientists and formulators, access to high-purity chemical intermediates is non-negotiable. 1-Chloro-3,5-di-(4-chlorobenzoyl)-2-deoxy-D-ribose, characterized by its unique deoxyribose structure adorned with chlorobenzoyl protecting groups, offers specific reactivity that is invaluable in organic synthesis. Its role is particularly prominent in the development of drugs like Decitabine, a compound that has shown significant promise in treating myelodysplastic syndromes. Beyond Decitabine, this intermediate is a gateway to exploring a wider array of nucleoside derivatives with potential antiviral, anticancer, and other therapeutic applications.

When considering the purchase of 1-Chloro-3,5-di-(4-chlorobenzoyl)-2-deoxy-D-ribose for research purposes, attention must be paid to its quality. Factors such as appearance (typically an off-white powder), assay purity (≥90.0%), and stability are crucial. Researchers often need to ensure that their starting materials have low levels of impurities, such as minimized loss on drying (≤2.0%) and residue on ignition (≤2.0%), to avoid complications in complex multi-step synthesis pathways. Identifying a reliable manufacturer or supplier that consistently delivers on these quality parameters is key to the success of any R&D project.

The global chemical market offers various avenues for procuring such specialized intermediates. Companies that focus on providing advanced pharmaceutical intermediates, often from established manufacturing bases like China, can be excellent resources. These suppliers not only offer competitive price points but also understand the critical nature of these compounds for the pharmaceutical industry. For those looking to buy this compound, seeking out suppliers who can provide detailed specifications and technical support can significantly enhance the research process. Inquiry for bulk quantities is also common for ongoing research programs or pilot studies.

The exploration of new nucleoside analogs is a dynamic area of pharmaceutical research. The utility of 1-Chloro-3,5-di-(4-chlorobenzoyl)-2-deoxy-D-ribose as a foundational intermediate allows scientists to design and synthesize novel molecules with potentially improved therapeutic profiles. Its availability from reliable sources ensures that innovation in this field can continue unhindered, leading to the development of next-generation pharmaceuticals. Engaging with a competent supplier can provide access not only to the product but also to market insights and potential collaborative opportunities.

In summary, 1-Chloro-3,5-di-(4-chlorobenzoyl)-2-deoxy-D-ribose is more than just a chemical compound; it is an enabler of pharmaceutical innovation. Its role in the synthesis of critical drugs and its potential for future discoveries make it a valuable asset for researchers worldwide. Sourcing this intermediate from reputable manufacturers and suppliers, particularly those offering competitive pricing and high quality, is essential for advancing nucleoside analog research.