The constant battle against fungal infections necessitates continuous innovation in antifungal drug development. Central to this effort is the reliable availability of high-quality chemical intermediates, such as 1H-Imidazol-1-ylacetonitrile (CAS 98873-55-3). This compound plays a pivotal role in the synthesis of several important antifungal APIs, most notably Luliconazole.

1H-Imidazol-1-ylacetonitrile is characterized by its molecular formula C5H5N3 and a molecular weight of 107.113. It typically appears as a white to off-white powder, with a high purity level (≥98.0% HPLC) that is essential for its use in pharmaceutical synthesis. Its chemical structure makes it an ideal precursor for introducing the imidazole moiety, a common feature in many antifungal agents.

For researchers and development scientists, understanding the synthesis and properties of 1H-Imidazol-1-ylacetonitrile is key to advancing new antifungal therapies. Its application in creating molecules that interfere with fungal cell wall synthesis by inhibiting lanosterol demethylase activity is well-documented. This makes it a valuable commodity for drug discovery and optimization projects.

When considering the purchase of CAS 98873-55-3 for your research and development needs, it is crucial to identify suppliers who can provide consistent quality and detailed technical documentation. Engaging with manufacturers and suppliers that specialize in pharmaceutical intermediates ensures you receive material that meets the stringent requirements of the pharmaceutical industry. This includes confirming specifications like loss on drying (≤0.5%) and total impurities (≤1.0%).

The availability of 1H-Imidazol-1-ylacetonitrile from reliable chemical manufacturers worldwide facilitates the ongoing research and commercial production of critical antifungal medications. By ensuring a stable supply of this intermediate, the pharmaceutical sector can continue to develop effective treatments for a wide range of fungal infections.