In the dynamic field of pharmaceutical research and development, the identification and utilization of key building blocks are fundamental to creating innovative therapies. 2,4-Dibromopyridine-1-oxide, identified by CAS number 117196-08-4, stands out as a significant heterocyclic intermediate with diverse applications in drug synthesis. Understanding its chemical properties and functional role is crucial for scientists and procurement specialists aiming to buy this compound.

Chemical Structure and Reactivity

2,4-Dibromopyridine-1-oxide is characterized by its pyridine ring, substituted with bromine atoms at the 2 and 4 positions, and an oxygen atom coordinated to the nitrogen atom, forming an N-oxide. This specific arrangement of functional groups imparts unique reactivity. The bromine atoms are susceptible to nucleophilic substitution and cross-coupling reactions, while the N-oxide group can influence the electronic properties of the ring and participate in specific transformations. This inherent versatility makes it an attractive starting material for complex molecule construction.

Applications in Pharmaceutical Intermediate Synthesis

The primary application of 2,4-Dibromopyridine-1-oxide lies in its use as a key intermediate for synthesizing a wide array of pharmaceutical compounds. Its dibrominated pyridine core can be selectively modified through various chemical reactions, allowing for the introduction of diverse functionalities. This enables the creation of novel drug candidates targeting various therapeutic areas. Researchers often seek to buy this compound for:

  • API Synthesis: As a precursor for the synthesis of Active Pharmaceutical Ingredients (APIs) with specific biological activities.
  • Medicinal Chemistry: Exploring new drug scaffolds and structure-activity relationships (SAR) by incorporating this pyridine moiety.
  • Process Development: Optimizing synthetic routes for existing or new pharmaceutical products.

For pharmaceutical companies looking to purchase this intermediate, ensuring high purity (typically 97%+) is non-negotiable to guarantee the efficacy and safety of the final drug product. Sourcing from reliable manufacturers, such as NINGBO INNO PHARMCHEM CO.,LTD., who can provide consistent quality and documentation, is essential.

Procurement Strategies for Pharmaceutical Buyers

When procuring 2,4-Dibromopyridine-1-oxide for pharmaceutical applications, buyers should prioritize suppliers that offer:

  • Quality Assurance: Certificates of Analysis (CoA) detailing purity and impurity profiles.
  • Regulatory Compliance: Adherence to good manufacturing practices (GMP) or relevant quality standards for intermediates.
  • Supply Chain Stability: A robust manufacturing process to ensure consistent availability.
  • Responsive Customer Service: Prompt responses to inquiries and efficient sample provision.

By focusing on these aspects, pharmaceutical companies can establish strong partnerships with suppliers and secure a critical component for their drug development pipeline. Purchasing from established Chinese chemical manufacturers often provides a balance of quality and cost-effectiveness.