In the complex world of pharmaceutical manufacturing, the quality of starting materials and intermediates directly dictates the success of the final API. 2-(7-Methoxynaphthalen-1-yl)ethanamine (CAS: 138113-09-4) plays a pivotal role as a key intermediate in the synthesis of Agomelatine, a well-known antidepressant. This article delves into the significance of this chemical compound, its specifications, and the considerations for pharmaceutical companies looking to purchase it for their manufacturing processes.

Understanding 2-(7-Methoxynaphthalen-1-yl)ethanamine

Chemical Name: 2-(7-Methoxynaphthalen-1-yl)ethanamine CAS Number: 138113-09-4 Molecular Formula: C13H15NO Molecular Weight: 201.26 Appearance: White Crystal Solid Purity: ≥99%

This compound is characterized by its naphthalene core with a methoxy group and an ethylamine side chain. Its precise chemical structure and high purity make it an ideal precursor for Agomelatine synthesis. As an intermediate, its physical and chemical properties are critical. The white crystalline solid appearance is a key visual indicator of quality, while the high purity ensures minimal side reactions and efficient conversion into the desired API.

Applications in Agomelatine Synthesis

The primary and most critical application of 2-(7-Methoxynaphthalen-1-yl)ethanamine is its use as a direct precursor in the multi-step synthesis of Agomelatine. This includes processes where it is reacted with other chemical reagents to build the final Agomelatine molecule. Pharmaceutical R&D scientists and production managers often search for this specific intermediate by its CAS number or chemical name to ensure they are sourcing the correct material for their synthesis pathways. For those looking to buy this compound, it’s important to note that its value lies entirely in its ability to be transformed into a high-value pharmaceutical product.

Finding Reliable Manufacturers and Suppliers

When procuring 2-(7-Methoxynaphthalen-1-yl)ethanamine, pharmaceutical companies need to partner with reliable manufacturers and suppliers. These suppliers should be able to guarantee consistent product quality, adherence to specifications, and a stable supply chain. Many leading chemical suppliers, particularly those based in major chemical manufacturing regions like China, offer this intermediate. When considering a purchase, inquire about the supplier's manufacturing capabilities, quality control procedures, and their ability to provide essential documentation for regulatory compliance. For bulk orders, competitive pricing is often available, making it cost-effective for large-scale API production.

The Value Proposition for Buyers

For pharmaceutical companies, sourcing high-quality 2-(7-Methoxynaphthalen-1-yl)ethanamine is not just about buying a chemical; it's about investing in the integrity and efficacy of their final drug product. A consistent supply of this intermediate ensures that production lines run without interruption, and the final API meets all quality benchmarks. By working with experienced manufacturers, companies can also gain insights into efficient synthesis routes and potential cost optimizations. If your company requires this crucial component for Agomelatine production, seeking out dedicated chemical suppliers who specialize in pharmaceutical intermediates is a strategic move.