The Role of 2-Amino-3-methyl-5-nitropyridine in Pharmaceutical Synthesis
In the realm of pharmaceutical development, the quest for novel and effective drug molecules relies heavily on a robust supply of high-quality chemical intermediates. One such crucial compound is 2-Amino-3-methyl-5-nitropyridine, identified by its CAS number 18344-51-9. This pyridine derivative serves as a fundamental building block in the synthesis of a wide array of potentially therapeutic agents. Its unique chemical structure, featuring both amine and nitro functional groups on a substituted pyridine ring, imparts a reactivity that is highly prized by medicinal chemists.
The utility of 2-Amino-3-methyl-5-nitropyridine in pharmaceutical synthesis stems from its capacity to undergo various chemical transformations, leading to complex molecular architectures. Researchers often leverage this intermediate to introduce specific pharmacophores or to construct heterocyclic systems that are common in many drug candidates. Its application can span the development of treatments for neurological disorders, anti-inflammatory agents, and antimicrobial compounds, among others. When engaging in drug discovery, the ability to buy 2-amino-3-methyl-5-nitropyridine with assured purity (typically ≥99.0%) is critical for reliable experimental results and scale-up.
For R&D scientists and procurement specialists in the pharmaceutical industry, identifying a trustworthy manufacturer and supplier for such intermediates is paramount. Proximity to a reliable manufacturer in China can often provide cost efficiencies, but diligence in quality control is essential. It's important to look for suppliers who can provide comprehensive documentation, including Certificates of Analysis (CoA) detailing purity and physical properties like melting point (249-253°C) and solubility. Understanding the compound's chemical name, such as 3-methyl-5-nitropyridin-2-amine, and its CAS number ensures accurate ordering.
When considering your purchasing needs, remember that the price of 2-Amino-3-methyl-5-nitropyridine can vary based on quantity, purity, and supplier. Securing a long-term supply agreement with a reputable vendor can mitigate risks and ensure a consistent flow of this indispensable intermediate for your ongoing pharmaceutical research and development projects. If your work involves complex organic synthesis for new drug discovery, ensure you partner with a supplier that prioritizes quality and reliability.
Perspectives & Insights
Logic Thinker AI
“Its unique chemical structure, featuring both amine and nitro functional groups on a substituted pyridine ring, imparts a reactivity that is highly prized by medicinal chemists.”
Molecule Spark 2025
“The utility of 2-Amino-3-methyl-5-nitropyridine in pharmaceutical synthesis stems from its capacity to undergo various chemical transformations, leading to complex molecular architectures.”
Alpha Pioneer 01
“Researchers often leverage this intermediate to introduce specific pharmacophores or to construct heterocyclic systems that are common in many drug candidates.”