In the dynamic world of chemical synthesis, specific molecular structures serve as indispensable lynchpins for creating advanced materials and therapeutics. 2-Amino-4-chloro-3-nitropyridine (CAS: 6980-08-1) is one such compound, highly valued for its utility in organic synthesis, particularly within the pharmaceutical and agrochemical industries. Understanding its chemical behavior and application potential is key for researchers and product developers.

Chemical Profile and Reactivity

2-Amino-4-chloro-3-nitropyridine, a substituted pyridine derivative, possesses a unique combination of functional groups – an amino group, a chlorine atom, and a nitro group – attached to the pyridine ring. This arrangement dictates its reactivity. The electron-withdrawing nature of the nitro group, coupled with the electron-donating effect of the amino group and the presence of the halogen, makes specific positions on the ring susceptible to various reactions. For example, the nitro group can undergo reduction, and the chlorine atom can be a site for nucleophilic substitution, expanding its use as a versatile building block.

Applications in Research and Development

The compound's primary utility lies in its role as an intermediate. It is instrumental in synthesizing 5-amino-azaoxindole derivatives and has been implicated in the preparation of pharmaceutically active compounds designed to treat proliferative disorders by modulating aurora kinase and FLT3 activity. Furthermore, its involvement in the synthesis of 1-deaza-6-methylthiopurine ribonucleoside highlights its potential in medicinal chemistry. For procurement, identifying a reliable manufacturer or supplier that can consistently deliver this compound is crucial for R&D continuity.

Purchasing Considerations for Scientists

Scientists and R&D professionals seeking to purchase 2-Amino-4-chloro-3-nitropyridine will find that availability and purity are key purchasing criteria. When you look to buy this chemical, consider suppliers who provide detailed specifications, including CAS number (6980-08-1), molecular weight, and purity data. Obtaining a quote from a trusted manufacturer in China can offer both cost-effectiveness and quality assurance. Understanding the handling and storage requirements, such as keeping it in a cool, ventilated place, also ensures its longevity and efficacy for synthesis projects.

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