In the intricate world of chemical synthesis, certain molecules emerge as indispensable tools, enabling the creation of complex and high-value compounds. 2-Bromo-4-fluoro-6-nitrophenol, identified by its CAS number 320-75-2, is one such molecule. Its unique structural configuration, featuring a strategically substituted phenolic ring, makes it a versatile building block with significant implications for the pharmaceutical, agrochemical, and specialty chemical industries. For R&D scientists and chemical engineers, understanding its role is crucial for unlocking new synthetic possibilities.

Understanding the Molecular Architecture

The chemical structure of 2-Bromo-4-fluoro-6-nitrophenol (C6H3BrFNO3) is key to its reactivity and utility. The molecule possesses:

  • A phenolic hydroxyl group (-OH), which can undergo esterification, etherification, or act as a nucleophile/electrophile depending on reaction conditions.
  • A bromine atom (-Br), a good leaving group and a site for cross-coupling reactions (e.g., Suzuki, Sonogashira).
  • A fluorine atom (-F), known for its ability to modulate electronic properties, lipophilicity, and metabolic stability in target molecules.
  • A nitro group (-NO2), an electron-withdrawing group that influences the reactivity of the aromatic ring and can be reduced to an amine for further derivatization.

This combination of functionalities allows for a wide array of synthetic transformations, making it a sought-after intermediate when researchers decide to buy chemicals for advanced projects.

Key Applications in Synthesis

The versatility of 2-Bromo-4-fluoro-6-nitrophenol (CAS 320-75-2) translates into diverse applications:

  • Pharmaceutical Synthesis: This compound is frequently employed in the synthesis of novel drug candidates. The strategic placement of substituents allows for precise modifications that can enhance a drug's efficacy, pharmacokinetics, and safety profile. It is a common intermediate in the creation of small molecule therapeutics targeting various diseases.
  • Agrochemical Development: In the agrochemical industry, it serves as a foundational component for developing new generations of pesticides, herbicides, and fungicides. The specific arrangement of halogens and the nitro group can impart desired biological activity and environmental persistence properties.
  • Material Science: The unique electronic and physical properties conferred by the fluorine and nitro groups can be leveraged in the design of functional materials, such as specialty polymers or advanced electronic components.
  • Research & Development: For organic chemists, 2-Bromo-4-fluoro-6-nitrophenol is a valuable tool for exploring new synthetic methodologies, reaction mechanisms, and structure-activity relationships. Its availability from reliable suppliers facilitates cutting-edge research.

Sourcing this Essential Intermediate

When embarking on synthesis projects requiring 2-Bromo-4-fluoro-6-nitrophenol, it is imperative to partner with reputable manufacturers and suppliers. Companies that offer high purity (typically 97-98%), reliable batch-to-batch consistency, and detailed analytical documentation (like COAs) are crucial. For cost-effective procurement, considering suppliers based in China can be highly beneficial, as they often provide competitive pricing and robust production capacities.

We, as a dedicated manufacturer and supplier of fine chemicals, pride ourselves on providing high-quality 2-Bromo-4-fluoro-6-nitrophenol (CAS 320-75-2). We encourage R&D professionals and procurement managers to reach out to us to buy this essential intermediate. Our commitment to quality, competitive pricing, and reliable supply ensures that your synthesis projects can proceed with confidence and efficiency.