The Role of 2-Bromo-6-fluoroaniline in Modern Drug Discovery
The journey from a promising compound to a life-saving drug is complex and relies heavily on the availability of high-quality chemical intermediates. Among these essential building blocks, 2-Bromo-6-fluoroaniline (CAS 65896-11-9) has emerged as a compound of significant interest in modern drug discovery. As a dedicated supplier of fine chemicals and pharmaceutical intermediates, we recognize the crucial role this molecule plays and aim to guide researchers and procurement professionals on its applications and the advantages of sourcing it reliably.
2-Bromo-6-fluoroaniline is a substituted aniline characterized by the presence of both a bromine atom and a fluorine atom ortho to the amine group. This specific arrangement of substituents imparts unique electronic and steric properties, making it an exceptionally useful synthon in organic chemistry. The bromine atom serves as an excellent leaving group, readily participating in various cross-coupling reactions, such as palladium-catalyzed couplings, which are fundamental to constructing carbon-carbon and carbon-heteroatom bonds. The fluorine atom, known for its ability to modulate lipophilicity, metabolic stability, and binding affinity, can significantly enhance the pharmacological profile of drug candidates. Consequently, this intermediate is frequently employed in the synthesis of novel therapeutic agents.
In pharmaceutical R&D, the need for consistency and purity is paramount. 2-Bromo-6-fluoroaniline, typically available with a minimum purity of 97%, ensures that chemists can proceed with their synthesis pathways with confidence. It is often utilized in the development of molecules targeting complex diseases, including certain types of cancer and inflammatory conditions. Researchers leverage its structural features to design molecules that can effectively interact with specific biological targets. For companies looking to buy this crucial component, partnering with a reputable chemical manufacturer based in China can provide access to high-quality materials at competitive prices, thereby optimizing research budgets and accelerating project timelines.
The versatility of 2-Bromo-6-fluoroaniline extends beyond its role in drug synthesis. It is also a valuable intermediate in the broader fine chemical industry, contributing to the creation of advanced materials and specialized chemicals. Its application in agrochemical formulations, for instance, can lead to the development of more potent and environmentally conscious crop protection agents. Furthermore, its unique chemical structure makes it a candidate for use in the electronics sector or in the creation of novel polymers. The ability to source this compound with consistent quality, often in bulk quantities, is a key enabler for innovation across these diverse fields.
When seeking to procure 2-Bromo-6-fluoroaniline, understanding its physical properties—such as its clear yellow to brown liquid appearance and a molecular weight of 190.01 g/mol—is essential for proper handling and application. As a leading supplier, we are committed to providing comprehensive product information and exceptional customer service. We invite you to explore our offerings and discover how our reliable supply chain and commitment to quality can support your research and manufacturing needs for this indispensable chemical intermediate. Contact us today to request a quote or sample.
Perspectives & Insights
Quantum Pioneer 24
“This specific arrangement of substituents imparts unique electronic and steric properties, making it an exceptionally useful synthon in organic chemistry.”
Bio Explorer X
“The bromine atom serves as an excellent leaving group, readily participating in various cross-coupling reactions, such as palladium-catalyzed couplings, which are fundamental to constructing carbon-carbon and carbon-heteroatom bonds.”
Nano Catalyst AI
“The fluorine atom, known for its ability to modulate lipophilicity, metabolic stability, and binding affinity, can significantly enhance the pharmacological profile of drug candidates.”