Innovation in the pharmaceutical and fine chemical sectors often hinges on the availability of sophisticated building blocks that enable the synthesis of complex molecules. 2-Bromophenylacetic Acid (CAS 18698-97-0) stands out as a particularly valuable intermediate due to its versatile chemical properties and broad applicability. For R&D scientists and procurement specialists, understanding its role and ensuring a reliable supply chain is key to driving progress. This article explores why 2-Bromophenylacetic Acid is indispensable for developing novel pharmaceuticals and advanced fine chemicals.

Chemical Properties and Synthetic Utility
2-Bromophenylacetic Acid, identified by CAS 18698-97-0, is a white to off-white crystalline solid. Its molecular architecture combines a phenylacetic acid core with a bromine atom substituted at the ortho position. This unique arrangement offers chemists a powerful tool for various synthetic transformations. The presence of the carboxylic acid group allows for easy derivatization into esters, amides, and acid halides, while the aryl bromide moiety is highly amenable to cross-coupling reactions such as Suzuki-Miyaura, Heck, and Sonogashira couplings. These reactions are fundamental in constructing complex carbon skeletons and introducing diverse functionalities, making it a cornerstone in the synthesis of novel organic compounds.

Applications in Pharmaceutical Research and Development
The pharmaceutical industry is a major consumer of 2-Bromophenylacetic Acid. Its utility lies in its role as a key intermediate for synthesizing Active Pharmaceutical Ingredients (APIs). Specifically, it has been implicated in the synthesis pathways of drugs targeting inflammatory conditions and other diseases. Researchers aiming to develop new therapeutic agents often buy 2-Bromophenylacetic Acid to:

  • Construct Novel Drug Candidates: Its structure can be readily modified to generate libraries of compounds for high-throughput screening.
  • Synthesize Anti-inflammatory Agents: Its derivatives have shown promise in preclinical studies for their anti-inflammatory activities.
  • Facilitate Complex API Synthesis: It acts as a critical starting material or intermediate in multi-step synthetic routes for established and new drugs.

Beyond Pharmaceuticals: Fine Chemicals and Materials Science
The versatility of 2-Bromophenylacetic Acid extends beyond pharmaceuticals. It is also a valuable intermediate in the production of fine chemicals, including those used in:

  • Agrochemicals: As a building block for pesticides or herbicides.
  • Materials Science: For creating specialty polymers, electronic materials, or functional dyes where specific aromatic structures are required.
  • Research Chemicals: As a reagent for academic research and method development in organic chemistry.

For those in the industry looking to buy 2-Bromophenylacetic Acid, it is essential to partner with reliable manufacturers who can guarantee purity, consistency, and a stable supply. As a dedicated supplier, we pride ourselves on offering high-quality 2-Bromophenylacetic Acid, manufactured to stringent standards. We understand the critical role this intermediate plays in driving innovation and are committed to supporting your R&D efforts with reliable products and competitive pricing. Inquire today to learn more about how our 2-Bromophenylacetic Acid can benefit your next project.