The Role of 2-Chloro-3',4'-dihydroxyacetophenone in Drug Discovery and Development
The journey from a novel molecule to a life-saving medication is a complex and multi-faceted process, heavily reliant on the availability of high-quality chemical intermediates. Among these crucial compounds, 2-Chloro-3',4'-dihydroxyacetophenone, identified by CAS number 99-40-1, plays a pivotal role, particularly in drug discovery and development. This article delves into its significance, applications, and the importance of sourcing it reliably.
With its molecular formula C8H7ClO3 and a molecular weight of approximately 186.59, 2-Chloro-3',4'-dihydroxyacetophenone is recognized for its versatile chemical structure. This includes a reactive chloroacetyl group and a catechol moiety, making it an ideal starting point for synthesizing a variety of biologically active molecules. Typically supplied in powder form with high purity (often 97% or 98%), it ensures the reliability and reproducibility required in pharmaceutical research and manufacturing.
One of the most significant contributions of 2-Chloro-3',4'-dihydroxyacetophenone to the pharmaceutical industry is its use as a key intermediate in the synthesis of hemostatic agents. It is a foundational component for producing Carbazochrome, a drug vital for controlling capillary bleeding and improving the tone of microvasculature. The consistent availability of this intermediate from manufacturers is therefore critical for ensuring the continuous supply of such essential medicines to patients worldwide.
Beyond its established applications, 2-Chloro-3',4'-dihydroxyacetophenone is increasingly being explored by researchers in drug discovery programs. Its chemical framework can be modified and elaborated upon to create novel compounds with potential therapeutic benefits. The catechol structure, known for its antioxidant properties, makes it a candidate for developing drugs that combat oxidative stress-related diseases. Medicinal chemists often seek to buy this chemical for its potential in developing new anti-inflammatory agents, analgesics, or other therapeutic compounds.
For pharmaceutical companies and research institutions, securing a dependable supply of 2-Chloro-3',4'-dihydroxyacetophenone is paramount. China has emerged as a leading global supplier of fine chemicals and pharmaceutical intermediates, offering competitive pricing and significant manufacturing capacity. When procurement professionals search for this compound, they often use terms like 'buy 2-chloro-3',4'-dihydroxyacetophenone' or 'cas 99-40-1 price in China,' seeking both quality and affordability. Establishing relationships with reputable Chinese manufacturers ensures access to high-purity materials and a stable supply chain.
The compound's potential extends to other areas of chemical research. Its reactivity profile makes it a valuable tool for exploring new synthetic methodologies. As researchers push the boundaries of chemistry, intermediates like this one become essential for creating complex molecular architectures and investigating new material properties.
In conclusion, 2-Chloro-3',4'-dihydroxyacetophenone (CAS 99-40-1) is an indispensable intermediate in the pharmaceutical industry, critical for the synthesis of important drugs and valuable for ongoing drug discovery efforts. Its high purity, versatile chemical nature, and availability from established manufacturers, particularly in China, make it a compound of choice for researchers and manufacturers alike. Engaging with trusted suppliers ensures the quality and consistency needed to drive innovation in medicine and chemistry.
Perspectives & Insights
Bio Analyst 88
“It is a foundational component for producing Carbazochrome, a drug vital for controlling capillary bleeding and improving the tone of microvasculature.”
Nano Seeker Pro
“The consistent availability of this intermediate from manufacturers is therefore critical for ensuring the continuous supply of such essential medicines to patients worldwide.”
Data Reader 7
“Beyond its established applications, 2-Chloro-3',4'-dihydroxyacetophenone is increasingly being explored by researchers in drug discovery programs.”