In the intricate world of pharmaceutical development, the quality and purity of chemical intermediates directly impact the success of the final drug product. (2-Chloro-5-iodophenyl)(4-fluorophenyl)methanone, identified by CAS number 915095-86-2, stands out as a critical intermediate, particularly recognized for its role in the synthesis of Empagliflozin. As a specialized manufacturer, understanding its chemical properties and its significance in drug synthesis is key to serving our clients effectively.

(2-Chloro-5-iodophenyl)(4-fluorophenyl)methanone is a substituted benzophenone derivative. Its molecular structure, C13H7ClFIO, with a molecular weight of 360.55, features specific halogen substituents and an ether linkage precursor that are vital for subsequent reactions in the Empagliflozin synthesis pathway. These structural elements are meticulously incorporated during its own synthesis, often involving Friedel-Crafts acylation reactions or similar electrophilic aromatic substitution methods, starting from precursors like 5-iodo-2-chlorobenzoic acid and fluorobenzene. Manufacturers meticulously control reaction conditions to ensure high yield and purity.

The primary application of this compound is as a key building block in the production of Empagliflozin, a potent and selective inhibitor of the sodium-glucose cotransporter 2 (SGLT2). Empagliflozin plays a significant role in managing type 2 diabetes by reducing glucose reabsorption in the kidneys, leading to lower blood glucose levels. The precise structural integrity of the (2-Chloro-5-iodophenyl)(4-fluorophenyl)methanone intermediate is therefore non-negotiable for the successful and efficient synthesis of this life-saving medication.

For research scientists and procurement managers looking to buy this compound, it is essential to source from suppliers who provide detailed chemical properties, including its melting point (typically 64-70°C), boiling point, and solubility characteristics. Knowing these details aids in formulation and reaction planning. Reliable suppliers also offer safety data sheets (SDS) and Certificates of Analysis (CoA) that detail purity, typically above 98% or 99%, confirmed by analytical techniques like HPLC and NMR. This level of detail ensures that the material is suitable for demanding pharmaceutical synthesis applications.

Our commitment as a manufacturer is to provide researchers and pharmaceutical companies with a dependable source for high-quality (2-Chloro-5-iodophenyl)(4-fluorophenyl)methanone. By offering this critical intermediate, we contribute to the advancement of pharmaceutical research and the availability of important therapeutic agents.