In the intricate landscape of pharmaceutical development, the selection of high-quality chemical intermediates is a non-negotiable aspect of success. Among these vital compounds, 2-Nitrobenzoic acid (CAS 552-16-9) stands out for its versatility and significance in various synthetic pathways. This article delves into its importance for R&D scientists and procurement specialists looking to buy this essential chemical.

2-Nitrobenzoic acid, often abbreviated as 2-NBA, is an organic compound with the molecular formula C7H5NO4. Its structure features a benzene ring with a nitro group and a carboxylic acid group attached at adjacent positions (ortho configuration). This ortho substitution is crucial for many of its chemical reactions and applications. The compound typically presents as a yellow powder crystal, with a high purity often specified as ≥99.5% for demanding pharmaceutical applications. Its melting point typically falls between 146-148°C, a key specification for quality control.

The primary utility of 2-Nitrobenzoic acid in the pharmaceutical sector is as a key intermediate. It serves as a building block for synthesizing Active Pharmaceutical Ingredients (APIs) and other complex organic molecules used in drug formulation. For instance, its nitro group can be reduced to an amino group, yielding anthranilic acid, which itself is a precursor for numerous pharmaceuticals and dyes. Researchers leverage 2-NBA for its ability to participate in reactions such as esterification, amidation, and condensation, which are fundamental to creating therapeutic agents.

When sourcing for pharmaceutical synthesis, it is imperative to engage with a reliable manufacturer and supplier. Companies like NINGBO INNO PHARMCHEM CO.,LTD. offer stringent quality assurance, ensuring that the 2-Nitrobenzoic acid meets pharmaceutical standards like USP, BP, and EP. This guarantees that the intermediate will perform predictably in synthesis, leading to reproducible results and compliant end products. Buyers often look for “high purity 2-nitrobenzoic acid for pharma synthesis” or “buy CAS 552-16-9 online” to find trusted sources.

Beyond its direct role in API synthesis, 2-Nitrobenzoic acid can also be involved in the development of novel drug delivery systems or as a reagent in specific analytical techniques used in drug quality control. The consistent availability and competitive price from established suppliers are also critical factors for research institutions and large-scale pharmaceutical manufacturers. Understanding the global market, particularly identifying key suppliers in China, can provide access to quality materials at optimized costs.

In summary, 2-Nitrobenzoic acid is an indispensable chemical intermediate for the pharmaceutical industry. Its chemical properties and reactivity make it a valuable tool for synthetic chemists. Prioritizing quality and reliability when selecting a manufacturer or supplier is paramount for successful drug development and production. For those seeking to purchase 2-Nitrobenzoic acid, thorough research into suppliers’ certifications, purity levels, and pricing structures is highly recommended.